139122-19-3
4-(2-Hydroxyethyl) Oxyindole
CAS: 139122-19-3
Molecular Formula: C10H11NO2
139122-19-3 - Names and Identifiers
| Name | 4-(2-Hydroxyethyl) Oxyindole |
| Synonyms | Ropinirole USP RC A Ropinirole EP Impurity F Ropinirole Intermediate 5 4-(2-hydroxyethoxy)indole 4-(2-hydroxyethyl)oxindole 4-(2-hydroxyethyl)oxyindole Ropinirol Related Compound A 4-(2-Hydroxyethyl) Oxyindole Ropinirole Related CoMpound A 4-(2-Hydroxyethyl)-2-oxoindole 4-(2-Hydroxyethyl)indolin-2-one 4-(2'-Hydroxyethyl)-2-oxoindole 4-(2-hydroxyethyl)-1H-indol-2-ol 4-(2'-Bromoethyl)-1,3-dihydro-2H-indol-2-one 1,3-dihydro-4-(2-hydroxyethyl)-2H-indol-2-one 4-(2-hydroxyethyl)-1,3-dihydro-2H-indol-2-one 1,3-Dihydro-4-(2-hydroxyethyl)-2H-indole-2-one 2H-indol-2-ONE, 1,3-dihydro-4-(2-hydroxyethyl)- 4-(2-hydroxyethyl)-1,3-dihydro-2H-indolin-2-one 4-(2'-hydroxyethyl)-1,3-dihydro-2H-indole-2-ONE Ropinirole Related Compound A (50 mg) (4-(2-hydroxyethyl)indolin-2-one) |
| CAS | 139122-19-3 |
| EINECS | 1312995-182-4 |
| InChI | InChI=1/C10H11NO2/c12-5-4-7-2-1-3-9-8(7)6-10(13)11-9/h1-3,12H,4-6H2,(H,11,13) |
| InChIKey | QRTHVOUKWCEPKJ-UHFFFAOYSA-N |
139122-19-3 - Physico-chemical Properties
| Molecular Formula | C10H11NO2 |
| Molar Mass | 177.2 |
| Density | 1.253±0.06 g/cm3(Predicted) |
| Melting Point | 148-150°C |
| Boling Point | 390.0±42.0 °C(Predicted) |
| Flash Point | 189.677°C |
| Solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | Yellow solid |
| Color | Pale Beige to Brown |
| pKa | 14.08±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.6 |
139122-19-3 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 42/43 - May cause sensitization by inhalation and skin contact. |
| Safety Description | 36/37 - Wear suitable protective clothing and gloves. |
| HS Code | 2933790002 |
139122-19-3 - Introduction
4-(2-Hydroxyethyl) oxindole is an organic compound with the chemical formula C11H9NO2.
Nature:
4-(2-hydroxyethyl) oxindole is a yellow solid with good crystalline properties. It has a high degree of solubility and stability.
Use:
4-(2-hydroxyethyl) oxindole is widely used in pharmaceutical field. It is an important synthetic intermediate, often used in the synthesis of bioactive compounds or drugs. In addition, it can also be used as a reagent for biochemical research.
Preparation Method:
The preparation of 4-(2-hydroxyethyl) oxindole is usually accomplished by chemical synthesis. A common method is to react indole with 2-chloroethanol under basic conditions to give 4-(2-hydroxyethyl) oxindole.
Safety Information:
4-(2-hydroxyethyl) oxindole has low toxicity and irritation under reasonable use conditions, but the following safety precautions should be paid attention:
1. use should wear protective gloves, goggles and other personal protective equipment, avoid direct contact with the skin and eyes.
2. experimental operation should be carried out in a well-ventilated place to avoid inhalation of dust or steam.
3. storage should be sealed, away from the fire and oxidant.
4. Comply with laboratory safety procedures and relevant regulations during use or handling.
Nature:
4-(2-hydroxyethyl) oxindole is a yellow solid with good crystalline properties. It has a high degree of solubility and stability.
Use:
4-(2-hydroxyethyl) oxindole is widely used in pharmaceutical field. It is an important synthetic intermediate, often used in the synthesis of bioactive compounds or drugs. In addition, it can also be used as a reagent for biochemical research.
Preparation Method:
The preparation of 4-(2-hydroxyethyl) oxindole is usually accomplished by chemical synthesis. A common method is to react indole with 2-chloroethanol under basic conditions to give 4-(2-hydroxyethyl) oxindole.
Safety Information:
4-(2-hydroxyethyl) oxindole has low toxicity and irritation under reasonable use conditions, but the following safety precautions should be paid attention:
1. use should wear protective gloves, goggles and other personal protective equipment, avoid direct contact with the skin and eyes.
2. experimental operation should be carried out in a well-ventilated place to avoid inhalation of dust or steam.
3. storage should be sealed, away from the fire and oxidant.
4. Comply with laboratory safety procedures and relevant regulations during use or handling.
Last Update：2024-04-09 20:52:54
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