1391835-53-2
1-[(4-Methylphenyl)sulfonyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
CAS: 1391835-53-2
Molecular Formula: C16H21BN2O4S
1391835-53-2 - Names and Identifiers
| Name | 1-[(4-Methylphenyl)sulfonyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole |
| Synonyms | 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-pyrazole 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-pyrazole 1-[(4-Methylphenyl)sulfonyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 1H-Pyrazole, 1-[(4-methylphenyl)sulfonyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- |
| CAS | 1391835-53-2 |
| InChI | InChI=1S/C16H21BN2O4S/c1-12-6-8-14(9-7-12)24(20,21)19-11-13(10-18-19)17-22-15(2,3)16(4,5)23-17/h6-11H,1-5H3 |
1391835-53-2 - Physico-chemical Properties
| Molecular Formula | C16H21BN2O4S |
| Molar Mass | 348.22 |
1391835-53-2 - Introduction
1-(4-Toluenesulfonyl)-1H-pyrazole-4-boronic acid ester is an organic compound with the following properties:
1. Appearance: A white to yellow solid.
2. melting point: about 82-86 ℃.
3. Solubility: Soluble in organic solvents such as chloroform, dimethyl sulfoxide and ether, slightly soluble in water.
The uses and applications of 1-(4-toluenesulfonyl)-1H-pyrazole-4-boronic acid ester include:
1. as a chemical intermediate: can be used to synthesize other organic compounds, such as drugs, pesticides, photosensitizers, etc.
2. as a light stabilizer: can be used in polymers, plastics and coatings and other products to improve its heat stability and light stability.
The method of preparing 1-(4-toluenesulfonyl)-1H-pyrazole-4-boronic acid ester is generally carried out by the following steps:
1. reaction: take 1-(4-toluene sulfonyl)-1H-pyrazole-4-borate sodium and the right amount of alcohol (such as methanol or isopropanol) reaction.
2. esterification: in an appropriate solvent, the reactants are added, and the reaction is heated until the reaction is completed.
3. Filtration: The reaction mixture was filtered and impurities removed.
4. Crystallization: The desired product is obtained by cooling or liquid phase precipitation.
Regarding the safety information of 1-(4-toluenesulfonyl)-1H-pyrazole-4-boronic acid ester, because it is an organic compound, the following should be paid attention to when using and storing:
1. avoid inhaling its dust or vapor, should wear appropriate protective equipment, such as protective glasses and respirator.
2. avoid skin contact, such as contact should immediately rinse with plenty of water, and seek medical help.
3. avoid ingestion, such as inadvertent intake, should immediately seek medical attention.
4. during use, maintain good ventilation conditions.
5. Storage should avoid contact with oxidants and strong acids and other substances to prevent reaction.
1. Appearance: A white to yellow solid.
2. melting point: about 82-86 ℃.
3. Solubility: Soluble in organic solvents such as chloroform, dimethyl sulfoxide and ether, slightly soluble in water.
The uses and applications of 1-(4-toluenesulfonyl)-1H-pyrazole-4-boronic acid ester include:
1. as a chemical intermediate: can be used to synthesize other organic compounds, such as drugs, pesticides, photosensitizers, etc.
2. as a light stabilizer: can be used in polymers, plastics and coatings and other products to improve its heat stability and light stability.
The method of preparing 1-(4-toluenesulfonyl)-1H-pyrazole-4-boronic acid ester is generally carried out by the following steps:
1. reaction: take 1-(4-toluene sulfonyl)-1H-pyrazole-4-borate sodium and the right amount of alcohol (such as methanol or isopropanol) reaction.
2. esterification: in an appropriate solvent, the reactants are added, and the reaction is heated until the reaction is completed.
3. Filtration: The reaction mixture was filtered and impurities removed.
4. Crystallization: The desired product is obtained by cooling or liquid phase precipitation.
Regarding the safety information of 1-(4-toluenesulfonyl)-1H-pyrazole-4-boronic acid ester, because it is an organic compound, the following should be paid attention to when using and storing:
1. avoid inhaling its dust or vapor, should wear appropriate protective equipment, such as protective glasses and respirator.
2. avoid skin contact, such as contact should immediately rinse with plenty of water, and seek medical help.
3. avoid ingestion, such as inadvertent intake, should immediately seek medical attention.
4. during use, maintain good ventilation conditions.
5. Storage should avoid contact with oxidants and strong acids and other substances to prevent reaction.
Last Update：2024-04-09 21:54:55
