1393350-27-0
DBCO-(CH2)2-NH2-CO-(CH2)3COOH-NHS
CAS: 1393350-27-0
Molecular Formula: C24H20N2O5
1393350-27-0 - Names and Identifiers
1393350-27-0 - Physico-chemical Properties
| Molecular Formula | C24H20N2O5 |
| Molar Mass | 416.43 |
1393350-27-0 - Introduction
DBCO-NHS ester (3) is a compound with important chemical properties. The following is a description of the properties, uses, preparation and safety information of DBCO-NHS ester 3:
Nature:
-Chemical name: 4-[[(2S)-2,6-dioxo-3,] oxy]-N,N-dimethyl-3-oxobutanamide
-Molecular formula: C11H12N3O6
-Molecular weight: 288.23g/mol
-Appearance: White solid powder
-Solubility: Soluble in organic solvents such as DMF, DMSO and acetonitrile
-Stability: It can be stored at room temperature for up to several months, but avoid exposure to a high humidity environment to prevent hydrolysis.
Use:
- DBCO-NHS ester 3 is an important coupling reagent for labeling biological molecules in biological systems, such as proteins, antibodies, oligonucleotides and peptides, for subsequent fluorescent staining, in situ hybridization, immunostaining and other analysis.
- DBCO-NHS ester 3 can react with alkynyl-containing compounds to form stable 1,2, 3-triazacycles, this reaction is called a Copper-free Click reaction with high selectivity and flexibility.
Preparation Method:
- DBCO-NHS ester 3 is usually prepared by reacting DBCO with NHS ester. The specific preparation method can refer to the relevant literature or professional manual, generally need some basic equipment and common reagents of Organic Synthesis Laboratory.
Safety Information:
- DBCO-NHS ester 3 is a chemical reagent used in laboratories. It needs to follow safe laboratory regulations and wear appropriate personal protective equipment, such as gloves, goggles and laboratory coats.
-Avoid direct contact with skin and inhalation of dust. During the operation, attention should be paid to prevent it from contacting with fire source or strong oxidant.
-For detailed safety information and operating instructions, please refer to the relevant safety data sheets (SDS) and laboratory safety operating procedures.
Nature:
-Chemical name: 4-[[(2S)-2,6-dioxo-3,] oxy]-N,N-dimethyl-3-oxobutanamide
-Molecular formula: C11H12N3O6
-Molecular weight: 288.23g/mol
-Appearance: White solid powder
-Solubility: Soluble in organic solvents such as DMF, DMSO and acetonitrile
-Stability: It can be stored at room temperature for up to several months, but avoid exposure to a high humidity environment to prevent hydrolysis.
Use:
- DBCO-NHS ester 3 is an important coupling reagent for labeling biological molecules in biological systems, such as proteins, antibodies, oligonucleotides and peptides, for subsequent fluorescent staining, in situ hybridization, immunostaining and other analysis.
- DBCO-NHS ester 3 can react with alkynyl-containing compounds to form stable 1,2, 3-triazacycles, this reaction is called a Copper-free Click reaction with high selectivity and flexibility.
Preparation Method:
- DBCO-NHS ester 3 is usually prepared by reacting DBCO with NHS ester. The specific preparation method can refer to the relevant literature or professional manual, generally need some basic equipment and common reagents of Organic Synthesis Laboratory.
Safety Information:
- DBCO-NHS ester 3 is a chemical reagent used in laboratories. It needs to follow safe laboratory regulations and wear appropriate personal protective equipment, such as gloves, goggles and laboratory coats.
-Avoid direct contact with skin and inhalation of dust. During the operation, attention should be paid to prevent it from contacting with fire source or strong oxidant.
-For detailed safety information and operating instructions, please refer to the relevant safety data sheets (SDS) and laboratory safety operating procedures.
Last Update：2024-04-10 22:29:15
