139481-28-0

139481-28-0 - Names and Identifiers

Name	BENZOIC ACID, 2-[[(2'-CYANO[1,1'-BIPHENYL]-4-YL)METHYL]AMINO]-3-NITRO-METHYL ESTER
Synonyms	CANDESARTAN CILEXETIL IMPURITY 8 Candesartan Cilexetil Impurity 8 4-yl)methyl]amino]-3-nitro-,methyl ester Benzoic acid, 2-[[(2'-cyano[1,1'-biphenyl]- CANDESARTAN INTERMEDIATES ( METHYL ESTER C4 ) methyl 2-((2'-cyanobiphenyl-4-yl)methylamino)-3-nitrobenzoate methyl 2-{[(2'-cyanobiphenyl-4-yl)methyl]amino}-3-nitrobenzoate methyl-2-[[(2'-cyanobiphenyl-4-yl)methyl]amino]-3-nitrobenzoate Methyl,2-[[(2'-Cyano[1,1'-Biphenyl]-4-yl)methyl]amino]-3-Nitro Benzoate 2-[[(2'-Cyano[1,1'-biphenyl]-4-yl)Methyl]aMino]-3-nitro-benzoic Acid Methyl Ester BENZOIC ACID, 2-[[(2'-CYANO[1,1'-BIPHENYL]-4-YL)METHYL]AMINO]-3-NITRO-METHYL ESTER
CAS	139481-28-0
InChI	InChI=1/C22H17N3O4/c1-29-22(26)19-7-4-8-20(25(27)28)21(19)24-14-15-9-11-16(12-10-15)18-6-3-2-5-17(18)13-23/h2-12,24H,14H2,1H3

139481-28-0 - Physico-chemical Properties

Molecular Formula	C22H17N3O4
Molar Mass	387.39
Density	1.33±0.1 g/cm3 (20 ºC 760 Torr)
Melting Point	133-135°C
Boling Point	595.5±50.0 °C(Predicted)
Flash Point	313.937°C
Solubility	Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
Vapor Presure	0mmHg at 25°C
Appearance	Solid
Color	Off-White to Light Yellow
pKa	-2.55±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.655

139481-28-0 - Introduction

Methyl ester C4, also known as methyl ether, is an organic compound. The following is a brief description of the nature, use, preparation and safety information of methyl ester C4:

1. nature:
Methyl ester C4 is a colorless liquid with a sweet taste and aroma. It has a low boiling point and flash point, volatile, and can be compatible with many organic solvents.

2. use:
Methyl C4 has a wide range of uses in industry, mainly including the following aspects:
-Manufacture of natural flavors and food flavors: Methyl ester C4 can be used as a solvent and diluent for synthetic flavors.
-Solvent: Because the methyl ester C4 has good solubility, it can be used as a solvent for the manufacturing process of paint, cleaning agent, ink and glue.
-chemical raw materials: methyl ester C4 is an important intermediate of many chemical reactions, which can be used to produce esters, ethers, acids and other compounds.
-Pharmaceutical manufacturing: Methyl ester C4 is used as an important raw material in the synthesis of certain drugs.

3. Preparation method:
The common method for preparing methyl ester C4 is through the esterification reaction of methanol and butanol (n-butanol or isobutanol). In the reaction, methanol reacts with butanol to produce methyl ester C4 and water, and common catalysts can promote the reaction.

4. Safety Information:
The use of methyl ester C4 requires attention to safety issues:
-Methyl ester C4 has flammable properties and avoids contact with open flames or high temperature substances.
-Avoid inhaling vapors of methyl ester C4 to avoid respiratory irritation and poisoning.
-Wear appropriate protective gloves and glasses when using methyl ester C4.
-Store away from fire and oxidant, and store in a well-ventilated place. In case of leakage, appropriate emergency measures and cleaning methods shall be taken promptly.

Last Update：2024-04-10 22:39:43