139585-48-1 - Names and Identifiers
139585-48-1 - Physico-chemical Properties
Molecular Formula | C6H6ClNO
|
Molar Mass | 143.57 |
Density | 1.210±0.06 g/cm3 (20 ºC 760 Torr) |
Boling Point | 213.7±20.0℃ (760 Torr) |
Flash Point | 83.1±21.8℃ |
Vapor Presure | 0.236mmHg at 25°C |
Appearance | Colorless to light yellow liquid |
pKa | -2.22±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.517 |
MDL | MFCD06659513 |
139585-48-1 - Risk and Safety
Hazard Symbols | Xn - Harmful

|
Risk Codes | 22 - Harmful if swallowed
|
139585-48-1 - Introduction
2-Chloro-5-methoxypyridine is an organic compound whose chemical formula is C6H6ClNO.
Nature:
-Appearance: Colorless liquid or crystalline solid
-Melting Point: 38-40°C
-Boiling Point: 153-154°C
-Density: 1.25g/cm³
-Solubility: can be dissolved in organic solvents such as ethanol, chloroform, dimethyl linolone
Use:
-2-Chloro-5-methoxypyridine is an important organic synthesis intermediate, which is widely used in pesticide, medicine and dye industry.
-In pesticides, it is often used as a raw material for pesticides and has good insecticidal activity.
-In the field of medicine, 2-chloro-5-methoxypyridine can be used for the synthesis of anti-viral, anti-cancer and anti-inflammatory drugs.
-In the dye industry, it can be used to synthesize halogenated ketone dyes.
Preparation Method:
The preparation of 2-chloro-5-methoxypyridine is usually obtained by reacting acetyl chloride with 2-methoxypyridine. The specific step is that acetyl chloride is first added into a reaction flask, and 2-methoxypyridine is added, and the reaction is carried out under appropriate conditions to generate the target product. After the reaction, the product can be purified by crystallization or solvent extraction.
Safety Information:
-2-Chloro-5-methoxypyridine is an organic compound with certain toxicity and should be used in accordance with safe operating procedures.
-Contact with skin, eyes or inhalation of vapors may cause irritation. Therefore, appropriate protective equipment such as gloves, goggles and respiratory protectors should be worn when using the compound.
-Store in a cool, dry place, away from fire and oxidizing agents.
-When handling the compound, pay attention to avoid contact with strong oxidants, strong acids and strong bases to avoid dangerous reactions.
Last Update:2024-04-09 20:48:19