13959-01-8

13959-01-8 - Names and Identifiers

Name	ethyl 3-bromopyridine-4-carboxylate
Synonyms	ethyl 3-bromoisonicotinate Ethyl 3-bromoisonicotinate ETHYL 3-BROMOPYRIDINE-4-CARBO ethyl 3-bromopyridine-4-carboxylate ETHYL 3-BROMOPYRIDINE-4-CARBOXYLATE 3-BroMopyridin-4-carboxylic acid ethyl ester 3-BROMOPYRIDINE-4-CARBOXYLIC ACID ETHYL ESTER 4-Pyridinecarboxylic acid, 3-broMo-, ethyl ester 4-pyridinecarboxylic acid, 3-bromo-, ethyl ester
CAS	13959-01-8
InChI	InChI=1/C8H8BrNO2/c1-2-12-8(11)6-3-4-10-5-7(6)9/h3-5H,2H2,1H3

13959-01-8 - Physico-chemical Properties

Molecular Formula	C8H8BrNO2
Molar Mass	230.06
Density	1.501±0.06 g/cm3(Predicted)
Boling Point	263.4±20.0 °C(Predicted)
Flash Point	113.09°C
Vapor Presure	0.01mmHg at 25°C
pKa	0.84±0.18(Predicted)
Storage Condition	2-8°C
Refractive Index	1.545

13959-01-8 - Introduction

Ethyl 3-bromopyridine-4-carboxylate is an organic compound with the chemical formula C9H8BrNO2 and a molecular weight of 249.07g/mol. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Ethyl 3-bromopyridine-4-carboxylate is a colorless to pale yellow liquid.
-Solubility: It can be dissolved in most organic solvents and is insoluble in water.
-Melting point: Its melting point is about -1°C.
-Boiling point: Its boiling point is about 256-258°C.

Use:
-3-Bromopyridine-4-carboxylic acid ethyl ester is often used as a raw material for organic synthesis.
-It can participate in different reactions, such as Heck reaction, Suzuki reaction, Stille reaction, etc.
-It can also be used to synthesize other organic compounds, such as pesticides and drugs.

Preparation Method:
The preparation method of ethyl 3-bromopyridine-4-carboxylate can be carried out by the following steps:
1. 3-bromopyridine and cuprous bromide are reacted in dimethylformamide (DMF) to form cupric 3-bromopyridine.
2. Under reflux conditions, ethyl formate and stannous carbonate are added to react to generate ethyl 3-bromopyridine-4-carboxylate.

Safety Information:
-3-Bromopyridine-4-carboxylic acid ethyl ester is an organic compound and should be operated in accordance with general laboratory safety procedures.
-It may irritate the eyes, skin and respiratory system, so avoid contact during operation.
-Care should be taken during use, including wearing appropriate protective goggles, gloves and protective clothing.
-During storage and handling, keep the container sealed and store in a cool, dry, and well-ventilated place.
-If inhaled or ingested, seek medical attention immediately. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-09 20:49:11