139962-95-1

139962-95-1 - Names and Identifiers

Name	4-Methoxy-2-formylphenylboronic acid
Synonyms	AKOS BRN-0106 RARECHEM AH PB 0117 2-Formyl-4-Methoxyphenylboroni 2-FORMYL-4-METHOXYPHENYLBORONIC ACID 4-Methoxy-2-formylphenylboronic acid 4-METHOXY-2-FORMYLPHENYLBORONIC ACID 2-Formyl-4-methoxyphenylboronic acid 2-Formyl-4-methoxybenzeneboronic acid 4-METHOXY-2-FORMYLBENZENEBORONIC ACID
CAS	139962-95-1
InChI	InChI=1/C8H9BO4/c1-13-7-2-3-8(9(11)12)6(4-7)5-10/h2-5,11-12H,1H3

139962-95-1 - Physico-chemical Properties

Molecular Formula	C8H9BO4
Molar Mass	179.97
Density	1.25±0.1 g/cm3(Predicted)
Melting Point	166-170 °C
Boling Point	395.2±52.0 °C(Predicted)
Flash Point	192.8°C
Solubility	soluble in Methanol
Vapor Presure	5.89E-07mmHg at 25°C
Appearance	powder to crystal
Color	White to Light yellow
pKa	8.61±0.53(Predicted)
Storage Condition	2-8°C
Refractive Index	1.537

139962-95-1 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany	3
Hazard Note	Irritant
Hazard Class	IRRITANT, KEEP COLD

139962-95-1 - Introduction

4-methoxy -2-formyl benzene boronic acid, chemical formula is C9H9BO4, is a kind of organic boron compound.

Its properties are as follows:
1. Appearance: colorless crystal or white crystalline powder;
2. melting point: about 135-137 degrees Celsius;
3. solubility: soluble in organic solvents such as ethanol and dichloromethane, slightly soluble in water;
4. Stability: Stable at room temperature, but avoid exposure to strong light.

4-Methoxy-2-formylphenylboronic acid has a variety of uses in chemical research and industrial preparation, including:
1. As a reagent for organic synthesis, it can be used to synthesize other compounds, such as organic borate esters;
2. in the pharmaceutical field, can be used for the preparation of pharmaceutical intermediates;
3. can be used as oxidizing agent, reducing agent and catalyst.

This compound can be prepared generally by reacting methyl iodide with phenylboronic acid in the presence of a base. The specific operation is as follows:
1. Dissolve methyl iodide and phenylboronic acid in ethanol under inert atmosphere;
2. add appropriate amount of alkali catalyst (such as sodium carbonate, potassium carbonate, etc.);
3. Reaction at room temperature for a period of time, usually several hours;
4. The product was filtered and crystallized from cold ether to give 4-methoxy-2-formylphenylboronic acid.

Regarding safety information, specific safety and toxicity data for 4-methoxy-2-formylphenylboronic acid may vary depending on the method of preparation and purity. In general, the operation should pay attention to the following safety matters:
1. avoid contact with the skin, if accidentally contact the skin, immediately rinse with plenty of water;
2. Avoid inhaling the dust or gas of the solution, and should be equipped with appropriate protective equipment, such as protective gloves, goggles and protective masks;
3. Operate in a well-ventilated place to avoid the accumulation of harmful gases;
4. Store away from high temperature, fire and strong light.

Due to the operational risks and safety factors of chemical substances, it is recommended to use them under the guidance of professionals and follow relevant safe operating procedures.

Last Update：2024-04-09 19:05:46