14027-75-9
3-Fluoro-5-nitrobenzoic acid
CAS: 14027-75-9
Molecular Formula: C7H4FNO4
14027-75-9 - Names and Identifiers
| Name | 3-Fluoro-5-nitrobenzoic acid |
| Synonyms | 3-Fluoro-5-NitrobenzoicAci 3-FLUORO-5-NITROBENZOIC ACID 3-Fluoro-5-nitrobenzoic acid Benzoic acid, 3-fluoro-5-nitro- |
| CAS | 14027-75-9 |
| InChI | InChI=1/C7H4FNO4/c8-5-1-4(7(10)11)2-6(3-5)9(12)13/h1-3H,(H,10,11) |
14027-75-9 - Physico-chemical Properties
| Molecular Formula | C7H4FNO4 |
| Molar Mass | 185.11 |
| Density | 1.568±0.06 g/cm3(Predicted) |
| Melting Point | 125°C |
| Boling Point | 341.2±27.0 °C(Predicted) |
| Flash Point | 160.1°C |
| Vapor Presure | 3.16E-05mmHg at 25°C |
| Appearance | Solid |
| pKa | 3.14±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.588 |
14027-75-9 - Introduction
3-fluoro-5-nitrobenzoic acid is an organic compound with the chemical formula C7H4FNO4. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: Yellow crystalline or powdery solid.
-Solubility: Soluble in organic solvents such as ethanol, acetone and dichloromethane, insoluble in water.
-Melting point: about 150-152 degrees Celsius.
-Stability: relatively stable at room temperature, but affected by conditions such as high temperature, light and strong oxidants.
Use:
-3-fluoro-5-nitrobenzoic acid is an important intermediate compound, which can be used to synthesize other organic compounds, such as pesticides, dyes and pharmaceutical intermediates.
-It is also used as a reference material and standard in research.
Preparation Method:
-3-fluoro-5-nitrobenzoic acid can be obtained by nitration of 3-fluoro-benzoic acid. First, 3-fluoro-benzoic acid was dissolved in concentrated sulfuric acid, and nitric acid was slowly added dropwise at a low temperature while maintaining the reaction temperature below 10 degrees Celsius. Then, the reaction mixture is cooled and the product is isolated by crystallization and dried to give 3-fluoro-5-nitrobenzoic acid.
Safety Information:
- 3-fluorine -5-nitrobenzoic acid is a chemical, with a certain degree of risk. It can cause irritation and damage to the eyes, skin and respiratory tract.
-Avoid contact with skin and eyes during handling and storage, and use appropriate personal protective equipment, such as laboratory gloves, goggles and protective masks.
-When handling the compound, it should be carried out in a well-ventilated environment to avoid excessive vapor or dust concentration.
-When using and handling, refer to the safety data sheets and operating instructions of the relevant chemicals, and follow laboratory and safe operating procedures.
Nature:
-Appearance: Yellow crystalline or powdery solid.
-Solubility: Soluble in organic solvents such as ethanol, acetone and dichloromethane, insoluble in water.
-Melting point: about 150-152 degrees Celsius.
-Stability: relatively stable at room temperature, but affected by conditions such as high temperature, light and strong oxidants.
Use:
-3-fluoro-5-nitrobenzoic acid is an important intermediate compound, which can be used to synthesize other organic compounds, such as pesticides, dyes and pharmaceutical intermediates.
-It is also used as a reference material and standard in research.
Preparation Method:
-3-fluoro-5-nitrobenzoic acid can be obtained by nitration of 3-fluoro-benzoic acid. First, 3-fluoro-benzoic acid was dissolved in concentrated sulfuric acid, and nitric acid was slowly added dropwise at a low temperature while maintaining the reaction temperature below 10 degrees Celsius. Then, the reaction mixture is cooled and the product is isolated by crystallization and dried to give 3-fluoro-5-nitrobenzoic acid.
Safety Information:
- 3-fluorine -5-nitrobenzoic acid is a chemical, with a certain degree of risk. It can cause irritation and damage to the eyes, skin and respiratory tract.
-Avoid contact with skin and eyes during handling and storage, and use appropriate personal protective equipment, such as laboratory gloves, goggles and protective masks.
-When handling the compound, it should be carried out in a well-ventilated environment to avoid excessive vapor or dust concentration.
-When using and handling, refer to the safety data sheets and operating instructions of the relevant chemicals, and follow laboratory and safe operating procedures.
Last Update：2024-04-09 21:01:54
