140369-67-1

140369-67-1 - Names and Identifiers

Name	4-(4-Fluorophenyl)phenylboronic acid
Synonyms	AKOS BRN-1038 4'-FLUORO-4-BIPHENYLBORONIC ACID 4'-Fluorobiphenyl-4-boronic acid 4'-fluorobiphenyl-4-ylboronic acid 4-(4-Fluorophenyl)phenylboronic acid (4'-fluoro-[1,1'-biphenyl]-4-yl)boronic acid Boronic acid, B-(4'-fluoro[1,1'-biphenyl]-4-yl)-
CAS	140369-67-1
InChI	InChI=1/C12H10BFO2/c14-12-7-3-10(4-8-12)9-1-5-11(6-2-9)13(15)16/h1-8,15-16H

140369-67-1 - Physico-chemical Properties

Molecular Formula	C12H10BFO2
Molar Mass	216.02
Density	1.25±0.1 g/cm3(Predicted)
Boling Point	382.3±44.0 °C(Predicted)
Flash Point	185.014°C
Vapor Presure	0mmHg at 25°C
Appearance	Solid
pKa	8.56±0.17(Predicted)
Storage Condition	Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.591

140369-67-1 - Introduction

4-(4-fluorophenyl) phenylboronic acid is an organic compound. It has the molecular formula C12H9BF and the structural formula PhBF2, where Ph represents a phenyl group.

Nature:
4-(4-Fluorophenyl) phenylboronic acid is a colorless crystal, soluble in organic solvents such as ethanol and dimethylformamide. It is relatively stable in air, but decomposes when heated.

Use:
4-(4-Fluorophenyl) phenylboronic acid is mainly used in the field of organic synthesis. It is often used as a ligand for organometallic catalysts to catalyze some important chemical reactions, such as coupling reactions and fluorination reactions. In addition, it can also be used to prepare other organoboron compounds.

Preparation Method:
The common preparation method is to react 4-fluorophenylboronic acid and phenylboronic acid under the catalysis of alkali. The reaction is generally carried out at elevated temperature with dehydration.

Safety Information:
4-(4-fluorophenyl) phenylboronic acid has low toxicity, but as an organic compound, it is still necessary to pay attention to safe operation. Contact with skin, eyes or inhalation of dust may cause irritation and eye irritation. Wear protective gloves and goggles during use and maintain well-ventilated laboratory conditions.

Last Update：2024-04-10 22:29:15