1410101-89-1
Propanedioic acid, 2-[(1R)-3-oxo-1-phenyl-3-[4-(trifluoroMethyl)phenyl]propyl]-
CAS: 1410101-89-1
Molecular Formula: C19H15F3O5
1410101-89-1 - Names and Identifiers
1410101-89-1 - Physico-chemical Properties
| Molecular Formula | C19H15F3O5 |
| Molar Mass | 380.31 |
| In vitro study | (R)-PS210 displays an AC 50 value of 1.8 μM towards PDK1 in a Cell-Free Kinase Activity Assay. And the maximum activation of PDK1 compared to DMSO control of (R)-PS210 is 5.5 fold. |
1410101-89-1 - References
| biological activity | (R)-PS210 is the R enantiomer of PS210 (compound 4h-eutomer), it is a substrate-selective allosteric activator of PDK1 with an AC50 value of 1.8 μm. (R)-PS210 targets the PIF binding pocket of pdk1. PIF: protein kinase C- related kinase 2 (PRK2) interacting fragment. |
| Target | AC50: 1.8 μm (PDK1) |
Last Update：2024-04-09 21:04:16
