14173-30-9

14173-30-9 - Names and Identifiers

Name	3-hydroxy-2-(hydroxymethyl)pyridine hydrochloride
Synonyms	AI3-61997 NSC 241173 TechnicalHCl 2-PYRIDINEMETHANOL HYDROCHLORIDE 3-HYDROXY-2-PYRIDINEMETHANOL HCL pyridin-2-ylmethanol hydrochloride 3-Hydroxy-2-(hydroxymethyl)pyridine HCl 3-Hydroxy-2-(Hydroxymethyl)Pyridine HCl 3-Hydroxy-2-pyridinemethanolhydrochloride 3-Hydroxy-2-pyridinemethanol hydrochloride 3-HYDROXY-2-PYRIDINEMETHANOL HYDROCHLORIDE 3-Hydroxy-2-Pyridinemethanol Hydrochloride 2-(hydroxymethyl)pyridin-3-ol hydrochloride 2-Pyridinemethanol, 3-hydroxy-, hydrochloride 3-Hydroxy-2-(hydroxymethyl)pyridine hydrochloride 3-hydroxy-2-(hydroxymethyl)pyridine hydrochloride 3-HYDROXY-2-(HYDROXYMETHYL)PYRIDINE HYDROCHLORIDE 3-HYDROXY-2-YDROXYMETHYLPYRIDINE HYDROCHLORIDE TECH
CAS	14173-30-9
EINECS	238-021-4
InChI	InChI=1/C6H7NO.ClH/c8-5-6-3-1-2-4-7-6;/h1-4,8H,5H2;1H
InChIKey	SKVRYQUMKJQZFN-UHFFFAOYSA-N

14173-30-9 - Physico-chemical Properties

Molecular Formula	C6H8ClNO2
Molar Mass	161.59
Melting Point	217°C (dec.)(lit.)
Boling Point	248.2°C at 760 mmHg
Flash Point	103.9°C
Vapor Presure	0.013mmHg at 25°C
Storage Condition	Inert atmosphere,Room Temperature

14173-30-9 - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S27 - Take off immediately all contaminated clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany	3

14173-30-9 - Introduction

3-Hydroxy-2-hydroxymethylpyridine hydrochloride, also known as DMHP (hydrochloride), is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: DMHP is a colorless crystalline powder.
-Solubility: DMHP has high solubility in water and is also soluble in ethanol and chloroform.
-Chemical properties: It is an alkaline substance that can react with acid to form the corresponding salt.

Use:
-Medicine: DMHP, as a drug intermediate, is commonly used in the synthesis of other pharmaceutical compounds, such as antihypertensive, antiviral and antitumor drugs.

Preparation Method:
- DMHP regular synthesis method: First, an excess of ethylenediamine is added through the reaction in 2-pyridinecarboxaldehyde, and the reaction is carried out at a higher temperature to form the DMHP product. Then, the hydrochloride salt is generated by adding acid.

Safety Information:
- DMHP may be toxic to humans. During handling and operation, care should be taken to avoid direct contact with skin, eyes and respiratory tract. Wear appropriate personal protective equipment, such as lab gloves, goggles and masks, as necessary.
-When using DMHP, it should be operated in a well-ventilated place to avoid prolonged exposure to high-concentration gases.
-Avoid contact with strong oxidants and flammable materials when using or storing DMHP to prevent unsafe chemical reactions.
-Pay attention to correct waste disposal methods and comply with relevant laws and regulations during disposal.

Last Update：2024-04-09 21:01:54