141761-83-3

141761-83-3 - Names and Identifiers

Name	6-Chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxylic acid methyl ester
Synonyms	2H-1,4-Benzoxazine-8-carboxylic methyl 6-chloro-4-methyl-3-oxo-1,4-benzoxazine-8-carboxylate 6-Chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-car... methyl 6-chloro-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-8-carboxylate Methyl 6-chloro-4-Methyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-carboxylate methyl 6-chloro-3,4-dihydro-4-methyl-3-oxo-2H-benzo[b][1,4]oxazine-8-carboxylate 6-Chloro-3,4-Dihydro-4-Methyl-3-Oxo-2H-1,4-Benzoxazine-8-CarboxylicAcidMethlyEster 6-Chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxylic acid methyl ester 6-chloro-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-8-carboxylic acid methyl ester 2H-1,4-Benzoxazine-8-carboxylicacid,6-chloro-3,4-dihydro-4-Methyl-3-oxo-, Methyl ester
CAS	141761-83-3
EINECS	1533716-785-6
InChI	InChI=1/C11H10ClNO4/c1-13-8-4-6(12)3-7(11(15)16-2)10(8)17-5-9(13)14/h3-4H,5H2,1-2H3

141761-83-3 - Physico-chemical Properties

Molecular Formula	C11H10ClNO4
Molar Mass	255.65
Density	1.384
Boling Point	498.8±45.0 °C(Predicted)
Flash Point	255.5°C
Vapor Presure	4.4E-10mmHg at 25°C
pKa	-1.00±0.20(Predicted)
Storage Condition	2-8°C
Refractive Index	1.568

141761-83-3 - Introduction

Methyl 6-chloro-3, 4-dihydro-4-methyl-3-oxo-2H-1, 4-benzoxazine-8-carboxylate is an organic compound also known as ketamine. Its chemical formula is C13H16ClNO2.

The compound has some of the following properties:
1. Appearance: Ketamine is a white crystalline solid, soluble in organic solvents such as methanol and chloroform.
2. melting point: the melting point of ketamine is between 260-263 ℃.
3. pH: Ketamine is an acidic compound with a pH of about 3.5-4.0.

The main use of ketamine is in the medical field, especially as an anesthetic and analgesic. It has the characteristics of rapid onset, short effect and controllable depth of anesthesia, and is used in anesthesia, emergency medical treatment and pain management of surgical means.

regarding the synthesis method of ketamine, there are many ways to choose, one of the typical methods is to react 4-methyl -1-phenyl -2-aza -2-butanone with hydrochloric acid to obtain the intermediate of ketamine, and then through further reaction and purification to obtain the final product.

When using and handling ketamine, you need to pay attention to the following safety information:
1. Ketamine is an anesthetic and analgesic for reasonable use by medical professionals only. Illegal use or abuse by individuals is prohibited.
2. in the use of ketamine, should be strictly in accordance with the medical guidance and dosage of use, to avoid excessive use or excessive use.
3. ketamine may have certain toxicity and side effects on the human body, such as respiratory depression, blood pressure drop, etc., so the patient's condition should be closely monitored during use.
4. When using ketamine, you should pay attention to prevent contact with eyes and skin. If you accidentally touch it, you should immediately rinse with plenty of water and seek medical help.

Last Update：2024-04-10 22:29:15