1423-27-4
2-Trifluoromethylphenylboronic acid
CAS: 1423-27-4
Molecular Formula: C7H6BF3O2
1423-27-4 - Names and Identifiers
| Name | 2-Trifluoromethylphenylboronic acid |
| Synonyms | AKOS BRN-0242 RARECHEM AH PB 0094 2-benzotrifluorideboronic acid O-TRIFLUOROMETHYLPHENYLBORONIC ACID 2-Trifluoromethylphenylboronic acid 2-(Trifluoromethyl)phenylboronic acid 2-(TRIFLUOROMETHYL)PHENYLBORONIC ACID 2-(TRIFLUOROMETHYL)BENZENEBORONIC ACID ALPHA,ALPHA,ALPHA-TRIFLUORO-O-TOLYLBORONIC ACID ALPHA,ALPHA,ALPHA-TRIFLUORO-O-TOLUENEBORONIC ACID |
| CAS | 1423-27-4 |
| EINECS | 640-203-7 |
| InChI | InChI=1/3C5H2F6O2.Bi.6H/c3*6-4(7,8)2(12)1-3(13)5(9,10)11;;;;;;;/h3*1,12H;;;;;;;/q;;;+3;;;;;;/p-3/b3*2-1-;;;;;;;/r3C5H2F6O2.BiH6/c3*6-4(7,8)2(12)1-3(13)5(9,10)11;/h3*1,12H;1H6/q;;;+3/p-3/b3*2-1- |
| InChIKey | JNSBEPKGFVENFS-UHFFFAOYSA-N |
1423-27-4 - Physico-chemical Properties
| Molecular Formula | C7H6BF3O2 |
| Molar Mass | 189.93 |
| Density | 1.36±0.1 g/cm3(Predicted) |
| Melting Point | 111-114 °C (lit.) |
| Boling Point | 274.5±50.0 °C(Predicted) |
| Solubility | slightly sol. in Methanol |
| Appearance | Solid |
| Color | White to Almost white |
| BRN | 2974465 |
| pKa | 8.11±0.58(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| MDL | MFCD00236059 |
1423-27-4 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29163990 |
| Hazard Class | IRRITANT |
1423-27-4 - Introduction
2-trifluoromethylbenzeneboronic acid, chemical formula C7H5BF3O2, is an organic boron compound. The following is a description of its nature, use, preparation and safety information:
Nature:
2-Trifluoromethylphenylboronic acid is a colorless to yellowish solid that is readily soluble in polar organic solvents such as ethanol, dimethyl sulfoxide and dimethylformamide at ambient temperature. It has high thermal and chemical stability.
Use:
2-Trifluoromethylphenylboronic acid is often used as an important reagent in organic synthesis. It can be used as a fluorinating reagent for the introduction of trifluoromethyl groups in chemical reactions. In addition, it is also often used as a catalyst, ligand and intermediate, participating in organic synthesis reactions, such as Su g reaction and C- H activation.
Preparation Method:
2-Trifluoromethylphenylboronic acid can be prepared by the following method:
1. bromotrifluoromethane and phenylboronic acid are reacted under alkaline conditions.
2. Trifluoromethylphenylboronic acid and potassium carbonate are reacted under alkaline conditions.
These methods are usually carried out in an inert atmosphere or in an inert solvent.
Safety Information:
2-Trifluoromethylphenylboronic acid is relatively safe under normal conditions of use, but the following matters still need to be noted:
1. Use should wear appropriate protective equipment, such as chemical goggles and gloves.
2. avoid contact with skin and eyes, avoid inhalation or ingestion.
3. Pay attention to good ventilation conditions during operation.
4. storage should be sealed container, and placed in a cool, dry place, avoid contact with oxygen, water and acid and alkali substances.
Please note that the above information is for reference only. Please refer to relevant safety data sheets and operating procedures before specific use, and follow relevant laws and regulations.
Nature:
2-Trifluoromethylphenylboronic acid is a colorless to yellowish solid that is readily soluble in polar organic solvents such as ethanol, dimethyl sulfoxide and dimethylformamide at ambient temperature. It has high thermal and chemical stability.
Use:
2-Trifluoromethylphenylboronic acid is often used as an important reagent in organic synthesis. It can be used as a fluorinating reagent for the introduction of trifluoromethyl groups in chemical reactions. In addition, it is also often used as a catalyst, ligand and intermediate, participating in organic synthesis reactions, such as Su g reaction and C- H activation.
Preparation Method:
2-Trifluoromethylphenylboronic acid can be prepared by the following method:
1. bromotrifluoromethane and phenylboronic acid are reacted under alkaline conditions.
2. Trifluoromethylphenylboronic acid and potassium carbonate are reacted under alkaline conditions.
These methods are usually carried out in an inert atmosphere or in an inert solvent.
Safety Information:
2-Trifluoromethylphenylboronic acid is relatively safe under normal conditions of use, but the following matters still need to be noted:
1. Use should wear appropriate protective equipment, such as chemical goggles and gloves.
2. avoid contact with skin and eyes, avoid inhalation or ingestion.
3. Pay attention to good ventilation conditions during operation.
4. storage should be sealed container, and placed in a cool, dry place, avoid contact with oxygen, water and acid and alkali substances.
Please note that the above information is for reference only. Please refer to relevant safety data sheets and operating procedures before specific use, and follow relevant laws and regulations.
Last Update：2024-04-10 22:29:15
Supplier List
Spot supply
Product Name: 2-(Trifluoromethyl)phenylboronic acid Visit Supplier Webpage Request for quotationCAS: 1423-27-4
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 2-(Trifluoromethyl)phenylboronic acid Visit Supplier Webpage Request for quotationCAS: 1423-27-4
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: 2-(Trifluoromethyl)phenylboronic acid Visit Supplier Webpage Request for quotation
CAS: 1423-27-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 1423-27-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: 2-(Trifluoromethyl)phenylboronic Acid Request for quotationCAS: 1423-27-4
Tel: 15001012717
Email: biz5@infsci.com
Mobile: 15001012717
QQ: 3007471201
Product List: View Catalog
Product Name: 2-Trifluoromethylphenylboronic acid Request for quotation
CAS: 1423-27-4
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: +8613651600618
WhatsApp: +8613651600618
CAS: 1423-27-4
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: +8613651600618
WhatsApp: +8613651600618
Spot supply
Product Name: 2-(Trifluoromethyl)phenylboronic acid Visit Supplier Webpage Request for quotationCAS: 1423-27-4
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 2-(Trifluoromethyl)phenylboronic acid Visit Supplier Webpage Request for quotationCAS: 1423-27-4
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: 2-(Trifluoromethyl)phenylboronic acid Visit Supplier Webpage Request for quotation
CAS: 1423-27-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 1423-27-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: 2-(Trifluoromethyl)phenylboronic Acid Request for quotationCAS: 1423-27-4
Tel: 15001012717
Email: biz5@infsci.com
Mobile: 15001012717
QQ: 3007471201
Product List: View Catalog
Product Name: 2-Trifluoromethylphenylboronic acid Request for quotation
CAS: 1423-27-4
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: +8613651600618
WhatsApp: +8613651600618
CAS: 1423-27-4
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: +8613651600618
WhatsApp: +8613651600618
View History