142606-53-9
CALCIUM CITRATE MALATE
CAS: 142606-53-9
Molecular Formula: C16H14Ca4O19
142606-53-9 - Names and Identifiers
| Name | CALCIUM CITRATE MALATE |
| Synonyms | Fruit acid calcium CALCIUM CITRATE MALATE Citric acid malic acid calcium 142606-53-9 CALCIUM CITRATE MALATE Calcium Citrate Malate Fine Granular 2-Hydroxy-1,2,3-propanetricarboxylic acid calcium salt mixt. with hydroxybutanedioic acid calcium salt |
| CAS | 142606-53-9 |
| InChI | InChI=1/2C6H8O7.C4H6O5.4Ca/c2*7-3(8)1-6(13,5(11)12)2-4(9)10;5-2(4(8)9)1-3(6)7;;;;/h2*13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);2,5H,1H2,(H,6,7)(H,8,9);;;;/q;;;4*+2/p-8 |
142606-53-9 - Physico-chemical Properties
| Molecular Formula | C16H14Ca4O19 |
| Boling Point | 309.6°C at 760 mmHg |
| Flash Point | 155.2°C |
| Vapor Presure | 5.73E-05mmHg at 25°C |
| Storage Condition | Room Temprature |
142606-53-9 - Risk and Safety
| HS Code | 2918195000 |
142606-53-9 - Reference Information
| overview | calcium fruit acid, also known as calcium malate citrate. As a new generation of high-quality calcium source that is popular in developed countries such as Europe and the United States, it is a crab compound formed by combining calcium, citric acid and malic acid in a certain proportion. It has now become the first choice in the United States, Western Europe and Japan. Highly absorbable calcium raw material. |
| application | calcium malate citrate is a calcium salt with variable composition of citric acid and malic acid. It is water-soluble and releases calcium ions and calcium citrate complexes into intestinal cells after dissolution. |
| characteristics | 1, high solubility through the solubility comparison experiment between calcium fruit acid and similar products, it is found that calcium fruit acid in similar products has moderate calcium content and solubility is obviously better than other products, and its solubility increases with the decrease of pH, and it still has good solubility in slightly alkaline and near-neutral environments. The high solubility of calcium fruit in a wide pH range is an important feature associated with high absorption. Temperature has little effect on its solubility, and its solubility is slightly higher at room temperature, so calcium fruit acid is more suitable as a calcium nutrient fortifier. However, the mechanism of calcium fruit acid with high solubility still needs to be discussed in depth. 2. High biological absorption and utilization The biggest feature of calcium fruit is that the calcium ingested by the human body has a high absorption rate. In addition, calcium fruit acid also has high biological utilization such as promoting bone formation and alleviating bone loss. The hyperabsorption of calcium fruit has been confirmed by animal experiments and clinical trials. Kobayashi and Yongye and others used rats to study the absorption balance of 45 Ca through the small intestine ligation ring experiment. The results showed that the in vivo retention rate of calcium from calcium fruit was 7810% and that of calcium carbonate was 2012%, showing the high absorption of calcium fruit. In addition, Smith et al. compared the absorption rates of CCM and calcium carbonate by double isotope method with 10 women aged 21-31 years old. The results showed that the absorption rate of calcium from calcium fruit acid was 3713%, which was significantly higher than that of calcium carbonate (2916%). Miller et al. conducted a clinical trial on the calcium absorption rate of calcium carbonate and calcium fruit acid in 12 adolescents aged 10 to 17 years old. The results also proved that calcium fruit acid has high absorption. Japan's Morita Suno male conducted a clinical calcium absorption rate comparison experiment on women aged 21-30: the results showed that for fresh orange juice with calcium fruit, the calcium absorption rate of the human body is 40%, which is much higher than that of milk with only 30% calcium absorption rate. Heaneg and others studied 361 postmenopausal women. The subjects were given placebo (p lacedo), calcium carbonate and calcium fruit acid for two years. The results showed that there was no significant difference between the groups within 5 years after menopause, but after 6 years, women with low calcium intake slowed down due to the decrease in bone mass administered with calcium, and the effect of slowing down the bone mass administered with calcium fruit was better than that of calcium carbonate. obvious. According to Wu Zhengqi and others, the components of calcium fruit acid citric acid and malic acid have an optical left-handed structure (the left-handed structure is an optically active compound structure that can be recognized by a biofilm), and it is a tricarboxylic acid cycle in the body. (TAC cycle) intermediate metabolites can ensure that calcium ions are slowly released with the oxidation of citric acid and malic acid in the body. This characteristic leads to high biological absorption and utilization of calcium fruit. 3. Reduce the obstacles to iron absorption Generally speaking, calcium will hinder the body's absorption of other minerals, while calcium fruit acid can reduce the body's obstacles to iron absorption. Deehr et al. studied the effect of calcium on iron absorption in 19 women aged 52-72 years. After the subjects ingested breakfast supplemented with 53 Fe, the intake of placebo, milk containing 500mg of calcium and fresh orange juice with calcium fruit were compared. The results showed that the retention order of 53 Fe was placebo (813%)> fresh orange juice containing calcium fruit (714%)> calcium fruit (610% ) > milk (314% ) , thus confirming that calcium fruit can indeed reduce the obstacle to iron absorption. |
| Use | Calcium fruit acid is an organic compound that can be used as a food additive. |
Last Update：2024-04-09 20:00:08
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CAS: 142606-53-9
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CAS: 142606-53-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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