142738-94-1
3-(TRIFLUOROMETHOXY)ANISOLE
CAS: 142738-94-1
Molecular Formula: C8H7F3O2
142738-94-1 - Names and Identifiers
| Name | 3-(TRIFLUOROMETHOXY)ANISOLE |
| Synonyms | 3-(TRIFLUOROMETHOXY)ANISOLE 1-METHOXY-3-(TRIFLUOROMETHOXY)BENZENE Benzene, 1-methoxy-3-(trifluoromethoxy)- |
| CAS | 142738-94-1 |
| InChI | InChI=1/C8H7F3O2/c1-12-6-3-2-4-7(5-6)13-8(9,10)11/h2-5H,1H3 |
142738-94-1 - Physico-chemical Properties
| Molecular Formula | C8H7F3O2 |
| Molar Mass | 192.14 |
| Density | 1.249 |
| Boling Point | 162℃ |
| Flash Point | 58℃ |
| Vapor Presure | 2.82mmHg at 25°C |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.434 |
142738-94-1 - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | 1993 |
| Hazard Note | Flammable |
| Hazard Class | IRRITANT, FLAMMABLE |
| Packing Group | III |
142738-94-1 - Introduction
3-(Trifluoromethoxy) anisole, chemical formula CH3OC6H4CF3, is an organic compound. The following is its nature, use, preparation and safety information:
Nature:
1. Appearance: 3-(trifluoromethoxy) anisole is a colorless to light yellow liquid.
2. Solubility: It is soluble in most organic solvents, such as alcohol, ether, etc., but its solubility in water is limited.
3. Stability: It is relatively stable at room temperature, but may decompose when heated.
Use:
1. as a solvent: 3-(trifluoromethoxy) anisole is commonly used as a solvent in organic synthesis because of its good solubility in organic solvents.
2. Drug intermediates: It can be used as one of the intermediates for the synthesis of various drugs, such as pesticides, antibiotics, etc.
Preparation Method:
3-(trifluoromethoxy) anisole has many preparation methods, and the following reactions can usually be used:
3-hydroxyanisole is esterified with trifluoromethyl alcohol in the presence of an acid catalyst to produce 3-(trifluoromethoxy) anisole.
Safety Information:
1. 3-(Trifluoromethoxy) anisole is a flammable liquid and should be avoided from exposure to open flames or high temperatures.
2 in use or storage, should avoid reaction with the oxidant, to prevent the occurrence of danger.
Nature:
1. Appearance: 3-(trifluoromethoxy) anisole is a colorless to light yellow liquid.
2. Solubility: It is soluble in most organic solvents, such as alcohol, ether, etc., but its solubility in water is limited.
3. Stability: It is relatively stable at room temperature, but may decompose when heated.
Use:
1. as a solvent: 3-(trifluoromethoxy) anisole is commonly used as a solvent in organic synthesis because of its good solubility in organic solvents.
2. Drug intermediates: It can be used as one of the intermediates for the synthesis of various drugs, such as pesticides, antibiotics, etc.
Preparation Method:
3-(trifluoromethoxy) anisole has many preparation methods, and the following reactions can usually be used:
3-hydroxyanisole is esterified with trifluoromethyl alcohol in the presence of an acid catalyst to produce 3-(trifluoromethoxy) anisole.
Safety Information:
1. 3-(Trifluoromethoxy) anisole is a flammable liquid and should be avoided from exposure to open flames or high temperatures.
2 in use or storage, should avoid reaction with the oxidant, to prevent the occurrence of danger.
Last Update：2024-04-09 21:04:16
