143262-17-3 - Names and Identifiers
Name | 7-BROMO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
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Synonyms | BOC-7-BROMOINDOLINE N-Boc-7-bromoindoline 1-Boc-7-bromoindoline 7-broMo-N-Boc-indoline tert-butyl 7-bromoindoline-1-carboxylate tert-butyl 7-bromo-2,3-dihydro-1H-indole-1-carboxylate 7-BROMO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 7-BROMO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTE... 1H-Indole-1-carboxylicacid, 7-broMo-2,3-dihydro-, 1,1-diMethylethyl ester
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CAS | 143262-17-3
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InChI | InChI=1/C13H16BrNO2/c1-13(2,3)17-12(16)15-8-7-9-5-4-6-10(14)11(9)15/h4-6H,7-8H2,1-3H3 |
143262-17-3 - Physico-chemical Properties
Molecular Formula | C13H16BrNO2
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Molar Mass | 298.18 |
Density | 1.4g/cm3 |
Boling Point | 349.9°C at 760 mmHg |
Flash Point | 165.4°C |
Vapor Presure | 4.55E-05mmHg at 25°C |
Storage Condition | 2-8°C |
Refractive Index | 1.57 |
143262-17-3 - Introduction
N-Boc-7-bromoindoline is an organic compound with the following properties:
Appearance: Usually a white solid.
molecular formula: C12H15BrNO2.
Molecular weight: 290.16g/mol.
N-Boc-7-bromoindoline has a wide range of applications in organic synthesis. It is an important intermediate commonly used in the preparation of amphetamine-like compounds, such as the antipsychotic drug olanzapine. In addition, it can also be used to synthesize other organic compounds of similar structure, expanding the field of chemical research and application.
The preparation method of N-Boc-7-bromoindoline generally comprises the following steps: reacting 7-bromoindoline with N-Boc-oxamic acid to generate the target product. For specific synthetic procedures, reference may be made to organic synthesis literature or synthetic manuals.
It is important to note the safety information when using N-Boc-7-bromoindoline. Because it is an organic bromine compound, it has certain toxicity and irritation. During operation, it is necessary to wear suitable protective equipment, such as gloves and goggles, to prevent contact with skin or eyes. In addition, during storage and disposal, it is necessary to follow relevant safety procedures, such as avoiding exposure to fire and avoiding contact with strong oxidizing agents.
Last Update:2024-04-09 21:04:16