143468-96-6

143468-96-6 - Names and Identifiers

Name	ethyl 2-carboxy-3-(2-thienyl)propionate
Synonyms	ethyl 2-carboxy-3-(2-thienyl)propionate 2-Carbethoxy-3-(2-thienyl)propanoic acid 2-Carbethoxy-3-(2-Thienyl)-Propionic Acid 2-(Ethoxycarbonyl)-3-(thien-2-yl)propanoic acid 2-(thiophen-2-ylmethyl)-malonic acid 1-ethyl ester (2-Thienylmethyl)propanedioic acid monoethyl ester 2-(2-ThienylMethyl)propanedioic Acid 1-Ethyl Ester 3-ethoxy-3-oxo-2-(thiophen-2-ylmethyl)propanoic acid 2-(2-THIENYLMETHYL) PROPANEDIOIC ACID MONOETHYL ESTER (SB201999)
CAS	143468-96-6
EINECS	415-680-8
InChI	InChI=1/C10H12O4S/c1-2-14-10(13)8(9(11)12)6-7-4-3-5-15-7/h3-5,8H,2,6H2,1H3,(H,11,12)

143468-96-6 - Physico-chemical Properties

Molecular Formula	C10H12O4S
Molar Mass	228.26
Density	1.295
Boling Point	170 °C(Press: 12.2 Torr)
Flash Point	172.7°C
Vapor Presure	7.16E-06mmHg at 25°C
pKa	2.67±0.34(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.548

143468-96-6 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R38 - Irritating to the skin R41 - Risk of serious damage to eyes R43 - May cause sensitization by skin contact
Safety Description	S24 - Avoid contact with skin. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection

143468-96-6 - Introduction

ethyl 2-carboxy-3-(2-thienyl)propionate, also known as ethyl (2-thienylmethyl) malonate, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
ethyl 2-carboxy-3-(2-thienyl)propionate is a colorless to light yellow liquid with a strong pungent odor at room temperature. It is soluble in many organic solvents, such as ethers, alcohols and aromatic hydrocarbons. It is chemically stable, but may decompose under light.

Use:
ethyl 2-carboxy-3-(2-thienyl)propionate is commonly used as an organic synthesis intermediate for the synthesis of other organic compounds, especially for the synthesis of compounds containing thiophene functional groups. It has a wide range of applications in the fields of medicine, pesticides, dyes and coatings.

Method:
The preparation of ethyl 2-carboxy-3-(2-thienyl)propionate is usually obtained by reacting thiophene Formic Anhydride with ethanol. Specific synthetic methods can be found in the chemical literature.

Safety Information:
ethyl 2-carboxy-3-(2-thienyl)propionate is irritating and volatile, and contact with skin and eyes should be avoided. Appropriate protective equipment such as gloves, goggles and protective clothing should be worn during operation. During storage and handling, the container should be kept away from fire and heat sources and kept tightly closed. If accidentally exposed or taken by mistake, seek medical attention immediately.

Last Update：2024-04-09 02:00:42