144120-53-6
fmoc-L-aspartic acid 1-allyl ester
CAS: 144120-53-6
Molecular Formula: C22H21NO6
144120-53-6 - Names and Identifiers
| Name | fmoc-L-aspartic acid 1-allyl ester |
| Synonyms | FMOC-ASP-OAL FMOC-ASP-OAI Fmoc-Asp-OAll FMOC-ASP-OALL Fmoc-Asp-allyl ester Fmoc-L-aspartic acid α-allyl ester fmoc-L-aspartic acid 1-allyl ester (9H-Fluoren-9-yl)MethOxy]Carbonyl Asp-OAll N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-ASPARTIC (3S)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-oxo-4-(prop-2-en-1-yloxy)butanoic acid (3S)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-oxo-4-(prop-2-en-1-yloxy)butanoic acid (non-preferred name) (2R)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-oxo-4-(prop-2-en-1-yloxy)butanoic acid (non-preferred name) |
| CAS | 144120-53-6 |
| EINECS | 276-252-2 |
| InChI | InChI=1/C22H21NO6/c1-2-11-28-20(24)12-19(21(25)26)23-22(27)29-13-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h2-10,18-19H,1,11-13H2,(H,23,27)(H,25,26)/t19-/m1/s1 |
144120-53-6 - Physico-chemical Properties
| Molecular Formula | C22H21NO6 |
| Molar Mass | 395.41 |
| Density | 1.286±0.06 g/cm3(Predicted) |
| Melting Point | 131.0 to 135.0 °C |
| Boling Point | 634.8±55.0 °C(Predicted) |
| Flash Point | 340°C |
| Vapor Presure | 3.52E-17mmHg at 25°C |
| Appearance | White powder |
| Color | White |
| BRN | 5460108 |
| pKa | 4.09±0.19(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.591 |
| MDL | MFCD00467715 |
144120-53-6 - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 2924 29 70 |
| Hazard Class | IRRITANT |
144120-53-6 - Introduction
fmoc-L-aspartic acid 1-allyl ester is a chemical reagent with the following properties:
1. Appearance: fmoc-L-aspartic acid 1-allyl ester is a white or off-white crystalline solid.
2. Use: fmoc-L-aspartic acid 1-allyl ester is mainly used for peptide synthesis in solid phase synthesis. It acts as an inducer for a protecting group (Fmoc protecting group) that allows selective protection of amino groups on amino acids. When preparing polypeptides, it can be used to protect the amino group of aspartic acid from reaction with other reagents.
3. Preparation method: fmoc-L-aspartic acid 1-allyl ester can be obtained by reacting Fmoc-L-aspartic acid with α-allyl alcohol in the presence of sodium carbonate. The reaction needs to be carried out under an inert atmosphere, such as under the protection of nitrogen. After completion of the reaction, column chromatography or crystallization purification is often used.
4. Security information: when using the fmoc-L-aspartic acid 1-allyl ester, you need to pay attention to the following security matters:
- fmoc-L-aspartic acid 1-allyl ester is a chemical agent, should avoid direct contact with the skin, inhalation or ingestion. Appropriate personal protective equipment such as lab gloves, goggles and lab coats should be worn during handling.
-This compound may cause irritation to the eyes, skin and respiratory system, so contact with these areas should be avoided during operation.
-It should be used under well-ventilated laboratory conditions to prevent the accumulation of toxic gases in the indoor air.
- fmoc-L-aspartic acid 1-allyl ester should be stored in a closed container, in a cool, dry place, away from fire and oxidizing agents.
1. Appearance: fmoc-L-aspartic acid 1-allyl ester is a white or off-white crystalline solid.
2. Use: fmoc-L-aspartic acid 1-allyl ester is mainly used for peptide synthesis in solid phase synthesis. It acts as an inducer for a protecting group (Fmoc protecting group) that allows selective protection of amino groups on amino acids. When preparing polypeptides, it can be used to protect the amino group of aspartic acid from reaction with other reagents.
3. Preparation method: fmoc-L-aspartic acid 1-allyl ester can be obtained by reacting Fmoc-L-aspartic acid with α-allyl alcohol in the presence of sodium carbonate. The reaction needs to be carried out under an inert atmosphere, such as under the protection of nitrogen. After completion of the reaction, column chromatography or crystallization purification is often used.
4. Security information: when using the fmoc-L-aspartic acid 1-allyl ester, you need to pay attention to the following security matters:
- fmoc-L-aspartic acid 1-allyl ester is a chemical agent, should avoid direct contact with the skin, inhalation or ingestion. Appropriate personal protective equipment such as lab gloves, goggles and lab coats should be worn during handling.
-This compound may cause irritation to the eyes, skin and respiratory system, so contact with these areas should be avoided during operation.
-It should be used under well-ventilated laboratory conditions to prevent the accumulation of toxic gases in the indoor air.
- fmoc-L-aspartic acid 1-allyl ester should be stored in a closed container, in a cool, dry place, away from fire and oxidizing agents.
Last Update：2024-04-09 21:21:28
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Spot supply
Product Name: Fmoc-Asp-Oall Visit Supplier Webpage Request for quotationCAS: 144120-53-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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