144564-95-4
C(Cbz)acetic acid
CAS: 144564-95-4
Molecular Formula: C14H13N3O5
144564-95-4 - Names and Identifiers
144564-95-4 - Physico-chemical Properties
| Molecular Formula | C14H13N3O5 |
| Molar Mass | 303.27 |
| Density | 1.39±0.1 g/cm3(Predicted) |
| Melting Point | 272-274 °C(Solv: methanol (67-56-1)) |
| pKa | 2.95±0.10(Predicted) |
144564-95-4 - Introduction
C(Cbz)acetic acid, also known as C(Cbz)acetic acid, is an organic compound. The following is an introduction to the nature, use, formulation and safety information of C(Cbz)acetic acid:
1. nature:
-Appearance: C(Cbz)acetic acid is colorless to white crystal or powder.
-Solubility: It can be dissolved in general organic solvents, such as ether, dimethylformamide, etc.
-Stability: C(Cbz)acetic acid is relatively stable at room temperature, but should avoid contact with strong oxidants.
2. use:
C(Cbz)acetic acid is commonly used as a protecting group in organic synthesis. It can be introduced onto an amine or hydroxyl group to form a stable protecting group to protect these functional groups from unwanted reactions during the reaction. C(Cbz)acetic acid can be protected in enols, amines and other compounds, and can be removed by appropriate deprotection reactions when necessary.
3. preparation method:
C(Cbz)acetic acid can usually be prepared by reacting the amine or hydroxyl group to be protected with N-bis-benzyloxycarbonyl cytosine. The reaction conditions can be selected according to specific experimental requirements, and common reaction conditions include alkaline conditions.
4. Safety Information:
The security of C(Cbz)acetic acid depends on its proper handling and use. During use, avoid direct contact with skin and eyes, and avoid inhaling its dust. Good ventilation and appropriate protective equipment such as lab gloves and goggles are required for operation. In addition, it should be stored and handled according to the specific situation to avoid reaction with strong oxidants or other hazardous chemicals. If necessary, the operation should be carried out under suitable facilities and the relevant safe operating procedures should be followed.
1. nature:
-Appearance: C(Cbz)acetic acid is colorless to white crystal or powder.
-Solubility: It can be dissolved in general organic solvents, such as ether, dimethylformamide, etc.
-Stability: C(Cbz)acetic acid is relatively stable at room temperature, but should avoid contact with strong oxidants.
2. use:
C(Cbz)acetic acid is commonly used as a protecting group in organic synthesis. It can be introduced onto an amine or hydroxyl group to form a stable protecting group to protect these functional groups from unwanted reactions during the reaction. C(Cbz)acetic acid can be protected in enols, amines and other compounds, and can be removed by appropriate deprotection reactions when necessary.
3. preparation method:
C(Cbz)acetic acid can usually be prepared by reacting the amine or hydroxyl group to be protected with N-bis-benzyloxycarbonyl cytosine. The reaction conditions can be selected according to specific experimental requirements, and common reaction conditions include alkaline conditions.
4. Safety Information:
The security of C(Cbz)acetic acid depends on its proper handling and use. During use, avoid direct contact with skin and eyes, and avoid inhaling its dust. Good ventilation and appropriate protective equipment such as lab gloves and goggles are required for operation. In addition, it should be stored and handled according to the specific situation to avoid reaction with strong oxidants or other hazardous chemicals. If necessary, the operation should be carried out under suitable facilities and the relevant safe operating procedures should be followed.
Last Update：2024-04-09 20:52:54
