14556-98-0

14556-98-0 - Names and Identifiers

Name	4-chloro-5-sulphamoylsalicylic acid
Synonyms	TIMTEC-BB SBB003139 4-Chlorosalicylic acid-5-sulfamide 4-CHLORO-5-SULFAMOYL SALICYLIC ACID 4-chloro-5-sulphamoylsalicylic acid 4-chloro-5-sulfamoyl salicylic acid 4-CHLOROSALICYLIC ACID-5-SULFONAMIDE 4-CHLORO-2-HYDROXY-5-SULFAMOYLBENZOIC ACID 4-chloro-2-hydroxy-5-sulfamoylbenzoic acid 4-chloro-2-hydroxy-5-(sulfamoylamino)benzoic acid
CAS	14556-98-0
EINECS	238-602-2
InChI	InChI=1/C7H6ClNO5S/c8-4-2-5(10)3(7(11)12)1-6(4)15(9,13)14/h1-2,10H,(H,11,12)(H2,9,13,14)

14556-98-0 - Physico-chemical Properties

Molecular Formula	C7H6ClNO5S
Molar Mass	251.64
Density	1.780±0.06 g/cm3(Predicted)
Melting Point	251-256 °C (dec.) (lit.)
Boling Point	528.4±60.0 °C(Predicted)
Flash Point	273.3°C
Solubility	DMSO (Slightly), Methanol (Slightly)
Vapor Presure	5.42E-12mmHg at 25°C
Appearance	White solid
Color	White to Off-White
pKa	2.01±0.10(Predicted)
Storage Condition	Sealed in dry,2-8°C
Refractive Index	1.654
MDL	MFCD00988990

14556-98-0 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3

14556-98-0 - Introduction

acid (4-CSA) is an organic compound with the following properties:

1. Appearance: 4-CSA is white crystalline powder.

2. Solubility: 4-CSA can be partially dissolved in water, and can be well dissolved in organic solvents (such as ethanol, dichloromethane, etc.).

3. Chemical properties: 4-CSA is stable to alkalis, acids and oxidants, but it will decompose at high temperatures.

4. Uses: 4-CSA is an important drug intermediate with a wide range of applications. It is often used in the synthesis of antibacterial drugs, fungicides, dyes and other chemicals.

5. Preparation method: preparation of 4-CSA usually use salicylic acid and chlorosulfonic acid reaction method. First, salicylic acid is dissolved in a suitable solvent at a suitable temperature, and then chlorosulfonic acid is gradually added. After completion of the reaction, the product obtained can be purified by Crystal separation and dried.

6. Safety Information: when using and operating 4-CSA, you need to pay attention to the following safety matters:
- 4-CSA is an irritant, avoid direct contact with skin and eyes.
-Avoid inhaling 4-CSA dust or gas, and ensure that the operation is carried out in a well-ventilated place.
-Use protective gloves and goggles, wash hands promptly after operation, and keep the work area clean.
-When storing 4-CSA, it should be placed in a dry and cool place, away from fire and flammable materials.
-In case of skin contact or ingestion, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-09 21:01:54