1456858-58-4
HG-9-91-01
CAS: 1456858-58-4
Molecular Formula: C32H37N7O3
1456858-58-4 - Names and Identifiers
| Name | HG-9-91-01 |
| Synonyms | HG-9-91-01 SIK INHIBITOR 1 1-(2,4-dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-[6-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]urea 1-(2,4-dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-(6-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)urea N-(2,4-Dimethoxyphenyl)-N'-(2,6-dimethylphenyl)-N-[6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]urea Urea, N-(2,4-dimethoxyphenyl)-N'-(2,6-dimethylphenyl)-N-[6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]- |
| CAS | 1456858-58-4 |
1456858-58-4 - Physico-chemical Properties
| Molecular Formula | C32H37N7O3 |
| Molar Mass | 567.68 |
| Density | 1.257±0.06 g/cm3(Predicted) |
| Boling Point | 790.8±60.0 °C(Predicted) |
| Solubility | 10 mM in DMSO |
| pKa | 13.11±0.70(Predicted) |
| Storage Condition | -20℃ |
1456858-58-4 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.762 ml | 8.808 ml | 17.616 ml |
| 5 mM | 0.352 ml | 1.762 ml | 3.523 ml |
| 10 mM | 0.176 ml | 0.881 ml | 1.762 ml |
| 5 mM | 0.035 ml | 0.176 ml | 0.352 ml |
Last Update：2024-01-02 23:10:35
1456858-58-4 - Reference Information
| biological activity | HG-9-91-01 (SIK inhibitor 1) is an effective and highly selective inhibitor of salt-inducible kinase (SIK). the IC50 values for SIK1, SIK2 and SIK3 are 0.92 nM, 6.6 nM and 9.6 nM respectively. |
| target | TargetValue SIK1 (Cell-free say) 0.92 nM SIK2 (Cell-free say) 6.6 nM SIK3 (Cell-free say) 9.6 nM |
| Target | Value |
| SIK1 (Cell-free assay) | 0.92 nM |
| SIK2 (Cell-free assay) | 6.6 nM |
| SIK3 (Cell-free assay) | 9.6 nM |
Last Update：2024-04-09 20:49:11
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Product Name: HG-9-91-01 Visit Supplier Webpage Request for quotationCAS: 1456858-58-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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