145951-26-4 - Names and Identifiers
145951-26-4 - Physico-chemical Properties
Molecular Formula | C8H8N2O2S
|
Molar Mass | 196.23 |
Density | 1.500 |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
145951-26-4 - Introduction
1H-Indole-6-sulfonamide(9CI), also known as indole -6-sulfonamide, is an organic compound with the chemical formula C9H8N2O2S. The following is an introduction to its nature, use, preparation and safety information:
Nature:
1H-Indole-6-sulfonamide(9CI) is a white or off-white crystalline powder, soluble in acids, alkalis and organic solvents such as alcohols and ethers, and insoluble in water. It decomposes at high temperature and has relatively low stability.
Use:
1H-Indole-6-sulfonamide(9CI) has important application value in organic synthesis. It can be used as an intermediate in organic synthesis for the synthesis of various compounds with biological activity. In the field of medicine, it can be used to synthesize anti-tumor drugs, hormone drugs, etc. In addition, it can also be used as a raw material in the field of dyes, optical materials, etc.
Method:
1H-Indole-6-sulfonamide(9CI) can be prepared by two main methods: one is to use chloroindole to react with sulfoxide to generate chloroindole sulfonamide, and then reduce to obtain 1H-Indole-6-sulfonamide(9CI). The second is by reacting indole and sulfonic anhydride with ammonia to Nitrogen heterocycle to give indole sulfonamide.
Safety Information:
Under the conditions of correct use and storage, the storage and operation of 1H-Indole-6-sulfonamide(9CI) is relatively safe. However, it may cause irritation to the eyes, skin and respiratory tract, so attention should be paid to protective measures during use, such as wearing appropriate protective glasses, gloves and masks. In addition, avoid contact with oxidizing agents and strong acids to prevent danger. When handling this compound, safety practices should be carefully observed. If ingestion or contact causes discomfort or adverse reactions, seek medical attention immediately.
Last Update:2024-04-09 20:52:54