14631-46-0

14631-46-0 - Names and Identifiers

Name	5,6,7,8-Tetrahydroquinolin-8-ol
Synonyms	in-8-oL Tetrahydro-quinolin-8-ol 5,6,7,8-Tetrahydroquinolin-8-ol 5,6,7,8-tetrahydro-8-Quinolinol 5,6,7,8-Tetrahydroquinoline-8-ol 5,6,7,8-TETRAHYDRO-QUINOLIN-8-OL 8-quinolinol,5,6,7,8-tetrahydro-
CAS	14631-46-0
InChI	InChI=1/C9H11NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h2,4,6,8,11H,1,3,5H2

14631-46-0 - Physico-chemical Properties

Molecular Formula	C9H11NO
Molar Mass	149.19
Density	1.179±0.06 g/cm3(Predicted)
Melting Point	64-65 °C
Boling Point	88-96 °C(Press: 2 Torr)
Flash Point	141°C
Vapor Presure	0.000274mmHg at 25°C
pKa	13.44±0.20(Predicted)
Storage Condition	2-8°C
Refractive Index	1.59

14631-46-0 - Risk and Safety

Hazard Symbols	T - Toxic
Risk Codes	25 - Toxic if swallowed
Safety Description	45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

14631-46-0 - Introduction

5,6, 7,8-tetrahydroquinolin-8-ol, also known as tetrahydroquinolin-8-ol, is an organic compound. The following is a description of some of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Usually colorless to light yellow crystals or crystalline powder.
-Solubility: Soluble in common solvents such as water, ethanol, benzene and chloroform.
-Melting point: About 102-105 ° C.
-molecular formula: C7H13NO.
-Molecular weight: 129.18g/mol.

Use:
-Pharmaceutical intermediates: 5,6, 7,8-tetrahydroquinolin-8-ol is commonly used as an intermediate in the synthesis of other active compounds in the pharmaceutical field.
-Biochemistry research: It is also used as a tool to study metabolic pathways and drug metabolism.

Method:
-Usually, 4-hydroxymorpholine can be reacted with bromoethane to generate 5-bromo-4-hydroxymorpholine, and then reacted with benzopyridine by heating and refluxing to generate 5-cyclobutene-1, 4-diketone derivatives. Finally, by treating this derivative with ammonia, 5,6, 7,8-tetrahydroquinolin-8-ol is produced.

Safety Information:
-There are few studies on the toxicity and danger of 5,6, 7,8-tetrahydroquinolin-8-ol, so it is necessary to pay attention to safe operation.
-When handling the compound, wear appropriate protective equipment, including laboratory gloves and protective glasses.
-Avoid inhalation, ingestion or skin contact to prevent accidental poisoning.
-During storage and handling, it should be kept separate from incompatible materials such as flammable materials and oxidants.
-Before use or disposal, it is recommended to consult the relevant safety data sheet for specific precautions for use and disposal.

Last Update：2024-04-09 21:00:56