146548-59-6

146548-59-6 - Names and Identifiers

Name	2,4,6-trimethoxybenzylamine hydrochloride
Synonyms	TIMTEC-BB SBB003257 2,4,6-Trimethoxybenz 2,4,6-TrimethoxybenzylamineHCl (2S)-2-amino-3-methylbutan-1-ol 1-(2,4,6-trimethoxyphenyl)methanamine 2,4,6-Trimethoxybenzylamine hydrochloride 2,4,6-trimethoxybenzylamine hydrochloride 2,4,6-TRIMETHOXYBENZYLAMINE HYDROCHLORIDE (2,4,6-triMethoxyphenyl)MethanaMine hydrochloride
CAS	146548-59-6
InChI	InChI=1/C10H15NO3/c1-12-7-4-9(13-2)8(6-11)10(5-7)14-3/h4-5H,6,11H2,1-3H3

146548-59-6 - Physico-chemical Properties

Molecular Formula	C10H16ClNO3
Molar Mass	233.69
Density	1.087g/cm³
Melting Point	204-207°C(lit.)
Boling Point	312°C at 760 mmHg
Flash Point	151.1°C
Vapor Presure	0.000544mmHg at 25°C
Appearance	Powder
Color	White to off-white
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.515

146548-59-6 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection
WGK Germany	3

146548-59-6 - Introduction

2,4,6-trimethoxybenzylamine hydrochloride is an organic compound with the chemical formula C10H15NO3 · HCl. The following is a description of some properties, uses, preparation and safety information about the compound:

Nature:
-Appearance: Colorless crystal or white crystalline powder.
-Solubility: Soluble in water, ethanol, chloroform and other organic solvents.
-Melting point: about 160-165°C.
-Density: about 1.18g/cm³.
- pKa: about 9.05 (in 10% aqueous solution).

Use:
- 2,4,6-trimethoxybenzylamine hydrochloride is mainly used as an intermediate and raw material in the field of medicine.
-It can be used to synthesize some drugs, such as antihypertensive drugs, stimulants and some anti-cancer drugs.
-It can also be used as a synthetic intermediate for biguanide drugs.

Method:
2,4,6-trimethoxybenzylamine hydrochloride can be prepared as follows:
-First, benzylamine is reacted with methanol in the presence of a base to obtain 2,4, 6-trimethoxybenzaldehyde.
-Then, 2,4, 6-trimethoxybenzaldehyde is reacted with hydrochloric acid to generate 2,4,6-trimethoxybenzylamine hydrochloride.

Safety Information:
- 2,4,6-trimethoxybenzylamine hydrochloride is a non-lethal chemical, but it is still necessary to pay attention to safe operation.
-Wear suitable personal protective equipment such as gloves, goggles and protective clothing during operation.
-Avoid inhaling its dust and avoid contact with skin and eyes.
-During use and storage, Please strictly abide by the relevant regulations on chemicals and store them in a dry and well-ventilated place.

Last Update：2024-04-09 21:01:54