Name | Novobiocin Sodium Salt |
Synonyms | Albamycinsodium Cathomycinsodium Novobiocin Sodium albamycin(capsule) Cathomycinsodiumlyovac Novobiocin Sodium Salt |
CAS | 1476-53-5 |
EINECS | 216-023-6 |
Molecular Formula | C31H35N2NaO11 |
Molar Mass | 634.61 |
Melting Point | 215-220 C |
Boling Point | 848.2℃ at 760mmHg |
Specific Rotation(α) | D24 -38° (c = 2.5 in 95% ethanol); D24 -33° (c = 2.5 in water) |
Water Solubility | Soluble in water at 100mg/ml. Also soluble in ethanol or DMSOSoluble in water, ethanol, dimethyldulfoxide and methanol. |
Solubility | DMSO 127 mg/mL Water 127 mg/mL Ethanol 127 mg/mL |
Appearance | Morphology White to yellow solid |
Color | white to faintly beige |
Merck | 13,6755 |
BRN | 3892910 |
PH | 7.5 (100g/l, H2O, 25℃) |
Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
Stability | Hygroscopic |
Physical and Chemical Properties | Bioactive Novobiocin Sodium (Albamycin, Cathomycin) is a very effective bacterial DNA gyrase and human organic anion transporter, acting on hOAT1,hOAT3 and hOAT4 with Ki of 14.87±0.40 μM, 4.77±1.12 μM and 90.50±7.50 μM, respectively. |
Risk Codes | R43 - May cause sensitization by skin contact R36 - Irritating to the eyes R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
Safety Description | S36 - Wear suitable protective clothing. S36/37 - Wear suitable protective clothing and gloves. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
WGK Germany | 2 |
RTECS | RD5425000 |
FLUKA BRAND F CODES | 8-10 |
HS Code | 2941 90 00 |
Toxicity | LD50 orally in Rabbit: 3500 mg/kg |