147732-56-7

147732-56-7 - Names and Identifiers

Name	N-1(1-oxohexadecyl-glycyl-L-histidyl-L-Lysine
Synonyms	PalmitoylTripeptide-1Pal-AHK Pal-GHK(PalMitoylTripeptide-1) N-(1-Oxohexadecyl)glycyl-L-histidyl-L-lysine N2-[(N-Palmitoylglycyl)-L-histidyl]-L-lysine N-1(1-oxohexadecyl-glycyl-L-histidyl-L-Lysine L-Lysine,N-(1-oxohexadecyl)glycyl-L-histidyl- N2-[N-[N-(1-oxohexadecyl)glycyl]-L-histidyl]-L-lysine
CAS	147732-56-7

147732-56-7 - Physico-chemical Properties

Molecular Formula	C30H54N6O5
Molar Mass	578.79
Density	1.105
Boling Point	913.0±65.0 °C(Predicted)
Storage Condition	-20℃
Use	Uses palmitoyl tripeptide -1 affects the synthesis of collagen, fibronectin and hyaluronic acid in human skin fibroblasts, and can be used for the preparation of anti-aging cosmetics.

147732-56-7 - Liquid-phase synthesis of palmitoyl tripeptide -1

from Palm Bridge research

patent type:

invention patent

Application (patent) number:

CN201810156010.2

application date:

20180223

Public/Announcement Number:

CN108218956A

Public/announcement date:

20180629

applicant (patent):

Guangzhou Tongjun Pharmaceutical Technology Co., Ltd.

inventor:

Zheng Qingquan

National and provincial code:

CN440106

Abstract:

The invention discloses a liquid phase synthesis method of palmitoyl tripeptide 1, the dipeptide fragment HHisLys(Z)OBzl and the other fragment PalGlyOH in the palmitoyl tripeptide 1 sequence were synthesized respectively, these two fragments were then used to synthesize a palmitoyl tripeptide fragment by activating the ester, and the final product palmitoyl tripeptide 1 was obtained by hydrogenation. The invention overcomes the disadvantages of protecting amino acids, many kinds of solvents, obvious excess of reagents and difficult recovery of solvents in each step of the solid phase reaction, and has the advantages of simple synthesis method and low product cost, more green to the environment and other advantages, and can be large-scale production, can be industrialized production of palmitoyl tripeptide 1.

Last Update：2024-01-02 23:10:35

147732-56-7 - Preparation solution concentration reference

	1mg	5mg	10mg
1 mM	1.728 ml	8.639 ml	17.277 ml
5 mM	0.346 ml	1.728 ml	3.455 ml
10 mM	0.173 ml	0.864 ml	1.728 ml
5 mM	0.035 ml	0.173 ml	0.346 ml

Last Update：2024-01-02 23:10:35

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