148546-99-0

148546-99-0 - Names and Identifiers

Name	3-(4-Methylpiperazin-1-yl)aniline
Synonyms	AKOS BB-8951 3-(4-Methypiperazin-1-yl)anilin 3-(4-Methylpiperazin-1-yl)aniline 3-(4-METHYLPIPERAZIN-1-YL)ANILINE 3-(4-Methyl-1-piperazinyl)aniline 3-(4-Methylpiperazin-1-yl)aniline 1-(3-Aminophenyl)-4-methylpiperazine 3-(4-methylpiperazin-1-yl)benzenamine Benzenamine, 3-(4-methyl-1-piperazinyl)- Benzenamine, 3-(4-methyl-1-piperazinyl)- (9CI)
CAS	148546-99-0

148546-99-0 - Physico-chemical Properties

Molecular Formula	C11H17N3
Molar Mass	191.27
Density	1.092±0.06 g/cm3(Predicted)
Melting Point	98-99
Boling Point	353.1±37.0 °C(Predicted)
Solubility	soluble in Methanol
Appearance	powder to crystal
Color	White to Yellow to Orange
pKa	7.88±0.42(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
MDL	MFCD08435857

148546-99-0 - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R34 - Causes burns
Safety Description	S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	2923
HS Code	29339900
Hazard Note	Corrosive
Hazard Class	8
Packing Group	III

148546-99-0 - Introduction

3-(4-Methylpiperazin-1-yl)aniline, also known as MPTP, is an organic compound. The following is an introduction to the nature, use, formulation and safety information of MPTP:

Nature:
MPTP is a white crystalline solid that is stable at room temperature. Its molecular formula is C12H16N2 and its molecular weight is 188.27g/mol. MPTP has strong oxalic acid and alkaline, soluble in water and organic solvents.

Use:
MPTP is mainly used in medical research, especially in the study of Parkinson's disease. MPTP can cause symptoms of Parkinson's disease, which is useful in animal models that mimic the disease. In addition, MPTP is also used to study the treatment of other nerve-related diseases.

Method:
The preparation of MPTP is usually carried out by chemical synthesis. A common method for the synthesis of MPTP is the introduction of methylpiperazinyl groups at the 2 and 4 positions of the aniline molecule.

Safety Information:
MPTP has high toxicity and can cause serious damage to the central nervous system. Therefore, it is necessary to take strict safety measures and follow the correct experimental procedures when operating MPTP. Exposure to MPTP in humans may result in central nervous system toxicity, including dyskinesia and nerve damage. Appropriate personal protective equipment should be worn to avoid direct contact with skin, eyes and respiratory tract when using or handling MPTP. At the same time, it should be operated in a well-ventilated laboratory environment to avoid its release into the air. In case of accidental exposure or inhalation of MPTP, seek professional medical help immediately.

Last Update：2024-04-10 22:29:15