149518-50-3

149518-50-3 - Names and Identifiers

Name	N-Boc-2-piperidineacetic acid
Synonyms	RARECHEM AK ML 0243 1-BOC-2-Piperidineacetic 1-BOC-2-PIPERIDINACETIC ACID N-BOC-2-PIPERIDINEACETIC ACID N-Boc-2-piperidineacetic acid 1-BOC-2-PIPERIDINEACETIC ACID 1-Boc-piperidine-2-acetic acid 1-N-Boc-2-piperidineacetic acid [1-(tert-butoxycarbonyl)piperidin-2-yl]acetic acid 2-CARBOXYMETHYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 2-[(2R)-1-[(2-methylpropan-2-yl)oxy-oxomethyl]-2-piperidinyl]acetate
CAS	149518-50-3
InChI	InChI=1/C12H21NO4/c1-12(2,3)17-11(16)13-7-5-4-6-9(13)8-10(14)15/h9H,4-8H2,1-3H3,(H,14,15)

149518-50-3 - Physico-chemical Properties

Molecular Formula	C12H21NO4
Molar Mass	243.3
Density	1.121g/cm³
Boling Point	373°C at 760 mmHg
Flash Point	179.4°C
Vapor Presure	1.37E-06mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.486
MDL	MFCD02179000

149518-50-3 - Risk and Safety

Hazard Symbols	T - Toxic
Risk Codes	25 - Toxic if swallowed
Safety Description	45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

149518-50-3 - Introduction

N-Boc-2-piperidineacetic acid, also known as TBOPA, is an organic compound. Its chemical formula is C11H17NO4 and its molecular weight is 227.26g/mol.

N-Boc-2-piperidineacetic acid is a solid with colorless to pale yellow crystals. It is an acidic compound that is readily soluble in water and organic solvents such as alcohols and ethers.

The compound is mainly used for carboxylic acid activating agent and protecting group in organic synthesis. It can be used in esterification reactions, acid chlorination reactions, acylation reactions and acylation reactions of carboxylic acids. In addition, it can be used as a protecting group for amino acids and saccharides.

The common method for preparing N-Boc-2-piperidineacetic acid is to react 2-piperidine acetic acid with tert-butoxycarbonyl chloroformate. The reaction is usually carried out at room temperature, and the resulting product can be isolated and purified by crystallization purification.

For safety information, N-Boc-2-piperidineacetic acid should follow the general chemical practice. It may cause irritation to the eyes, skin and respiratory system and direct contact should be avoided. During use, appropriate safety precautions, such as lab gloves, goggles and laboratory ventilation, should be worn. When stored, it should be kept in a dry, dark and sealed container.

Last Update：2024-04-10 22:29:15