15-ACETYLVOMITOXIN
15-Acetyl Deoxynivalenol
CAS: 88337-96-6
Molecular Formula: C17H22O7
15-ACETYLVOMITOXIN - Names and Identifiers
15-ACETYLVOMITOXIN - Physico-chemical Properties
| Molecular Formula | C17H22O7 |
| Molar Mass | 338.35 |
| Density | 1.42±0.1 g/cm3(Predicted) |
| Boling Point | 538.6±50.0 °C(Predicted) |
| Flash Point | 2°C |
| Appearance | neat |
| pKa | 11.83±0.70(Predicted) |
| Storage Condition | 2-8°C |
15-ACETYLVOMITOXIN - Risk and Safety
| Risk Codes | R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R36 - Irritating to the eyes R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R11 - Highly Flammable |
| Safety Description | S36/37 - Wear suitable protective clothing and gloves. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S16 - Keep away from sources of ignition. |
| UN IDs | UN 2811 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | YD0155000 |
| HS Code | 29329990 |
| Hazard Class | 6.1(a) |
| Packing Group | I |
15-ACETYLVOMITOXIN - Reference Information
| Overview | 15-O-acetodeoxycitrate falciol is an acetylated derivative of deoxycitrate falciol. DON (deoxynivalenol, DON) is a kind of trichothecene toxin produced by Fusarium in cereals. DON has a variety of biological activities. Studies have shown that DON can reduce the intracellular GRP78 level by inducing the degradation of GRP78. |
| Preparation | Dissolve DON(79.0mg,0.27mmol) in 50mL of anhydrous dichloromethane, add pyridine (1 mL) and 4-DMAP (about 10 mg), and then add acetic anhydride (27.2 mg,0.27mmol) drop by drop. The reaction was stirred overnight, treated with 20mL HCl(2N), and extracted 3 times with 50ml of dichloromethane. After drying with sodium sulfate, the solvent is filtered and evaporated. The remaining residues were subjected to column chromatographic separation (CHCl3:MeOH = 95:5) to obtain 15-ADON, I. e. 15-O-acetyldeoxycitrol (42.0 mg,47%,). |
| Biological activity | 15-Acetyl-deoxynivalenol is a highly toxic trichothecene found in grains, which is toxic to HepG2 cells. |
Last Update：2024-04-10 22:41:30
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Product Name: 15-Acetyl Deoxynivalenol Visit Supplier Webpage Request for quotationCAS: 88337-96-6
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Mobile: 18021002903
QQ: 3008007409
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