150969-56-5

150969-56-5 - Names and Identifiers

Name	5-(Trifluoromethyl)-1-indanone
Synonyms	5-trifluormethyl-1-indanone 5-(TRIFLUOROMETHYL)INDANONE 5-(Trifluoromethyl)-1-indanone 5-(TRIFLUOROMETHYL)-2,3-DIHYDROINDEN-1-ONE 5-(trifluoromethyl)-2,3-dihydro-1H-inden-1-one 5-(TrifluoroMethyl)-2,3-dihydro-1H-inden-1-one 1H-Inden-1-one, 2,3-dihydro-5-(trifluoromethyl)- 2,3-Dihydro-5-(trifluoromethyl)-1H-inden-1-one, 2,3-Dihydro-1-oxo-5-(trifluoromethyl)-1H-indene
CAS	150969-56-5
InChI	InChI=1/C10H7F3O/c11-10(12,13)7-2-3-8-6(5-7)1-4-9(8)14/h2-3,5H,1,4H2

150969-56-5 - Physico-chemical Properties

Molecular Formula	C10H7F3O
Molar Mass	200.16
Density	1.347±0.06 g/cm3(Predicted)
Boling Point	237.1±40.0 °C(Predicted)
Flash Point	95.3°C
Vapor Presure	0.0458mmHg at 25°C
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.497

150969-56-5 - Introduction

5-(Trifluoromethyl)-1-indanone (also known as TFMK) is an organic compound with the chemical formula C9H5F3O and a molecular weight of 188.13. It is a white crystalline solid with a unique aroma at room temperature.

5-(Trifluoromethyl)-1-indanone is commonly used in catalytic reactions in organic synthesis and drug research. It can be used as an important catalyst and has a wide range of applications in the synthesis of drugs and natural products. In addition, it can also be used as a standard material for trace analysis.

There are generally two methods for preparing 5-(Trifluoromethyl)-1-indanone. One common method is to react 1-indanone with trichloromethane under acidic conditions, followed by hydrofluoric acid treatment to obtain the product. Another method is to react 1-indanone with trifluoromethylsulfonyl fluoride under acidic conditions, followed by distillation purification to obtain the target product.

Regarding safety information, 5-(Trifluoromethyl)-1-indanone needs to pay attention to safety protection measures during operation. It is a flammable solid that will burn and release toxic fluoride gas when exposed to an open flame or high temperature. Avoid inhalation of its vapors and contact with skin during use. At the same time, the compound should be stored and handled properly to avoid mixing with oxidants, acids and combustibles. To ensure safety, read and follow the relevant safety guidelines and recommendations before using 5-(Trifluoromethyl)-1-indanone.

Last Update：2024-04-09 21:11:58