151135-64-7

151135-64-7 - Names and Identifiers

Name	4'-Hydroxy-2,4-dimethoxychalcone
Synonyms	4-O-Methylechinatin 4'-Hydroxy-2,4-dimethoxychalcone 2-Propen-1-one, 3-(2,4-dimethoxyphenyl)-1-(4-hydroxyphenyl)-, (2E)-
CAS	151135-64-7

151135-64-7 - Physico-chemical Properties

Molecular Formula	C17H16O4
Molar Mass	284.31
Appearance	Yellow powder
Storage Condition	2-8℃
In vitro study	4'-Hydroxy-2,4-dimethoxychalcone (compound 2) is against P. falciparum D6 (IC 50 =4.2 μM) and W2 (IC 50 =4.8 μM).
In vivo study	4'-Hydroxy-2,4-dimethoxychalcone (compound 2; oral; 160 mg/kg) has a T 1/2 of 1.94 hours, a C max of 158 ng/mL and an AUC of 384 ng•h/mL in four- to five-week-old ICR mice.

151135-64-7 - Reference Information

biological activity

4 '-Hydroxy-2,4-dimethoxychalcone is a natural chalcone derivative in the red herb resin of the dragon's blood geranium. 4 '-Hydroxy-2,4-dimethoxychalcone has a wide range of biological activities, including antimalarial, antiprotozoal, antibacterial, antifungal activity.

Last Update：2024-04-09 20:52:54