151157-53-8 - Names and Identifiers
151157-53-8 - Physico-chemical Properties
151157-53-8 - Introduction
1-[4-(Trifluoromethoxy)phenyl]cyclobutanecarboxylic Acid is an organic compound containing a cyclobutane and a phenyl group in its structure. The following is a detailed description of its nature, use, formulation and safety information:
Nature:
-Appearance: A white solid
-Solubility: The compound is easily soluble in common organic solvents such as ethanol and dimethylformamide
-Melting point: approximately between 100°C and 105°C
-Molecular formula: C13H13F3O2
-Molecular weight: 274.24g/mol
Use:
1-[4-(Trifluoromethoxy)phenyl] cyclostatin Acid is often used as a pharmaceutical intermediate in organic synthesis and can be used to prepare various organic compounds, such as drugs, pesticides, dyes and optical compounds, etc.
Method:
1-[4-(Trifluoromethoxy)phenyl] cycloputanecarboxyclic Acid can be prepared by the following steps:
1. First, Cyclobutane is reacted with quinoline bromide to generate a cyclobutenoquinoline compound.
2. Next, the cyclobutenoquinoline compound is reacted with trifluoromethyl alcohol to produce a 1-[4-(trifluoromethoxy) phenyl] cyclobutenoquinoline compound.
3. Finally, 1-[4-(Trifluoromethoxy)phenyl] cyclobutenoquinoline compound is oxidized under the catalysis of base to generate 1-[4-(Trifluoromethoxy)phenyl]cyclobutanecarboxylic Acid.
Safety Information:
1-[4-(Trifluoromethoxy)phenyl]cyclobutanecarboxylic Acid is a chemical that needs to be handled safely.
-Inhalation: Avoid inhalation to produce dust, gas or spray. Operate in a well-ventilated area.
-Ingestion: Prevent ingestion and seek medical attention immediately if ingested.
-Eye Contact: Immediately after exposure to chemicals, rinse with plenty of water for at least 15 minutes while seeking medical attention.
-Skin Contact: Immediately after exposure to chemicals, wash contaminated skin thoroughly with soap and water.
-Storage: Store in a dry, clean place, away from combustion sources and oxidants.
Please note that when using chemicals, always follow correct safe operating procedures and comply with national and local regulations.
Last Update：2024-04-09 21:01:54