152211-15-9

152211-15-9 - Names and Identifiers

Name	2-fluoro-6-(trifluoromethyl)benzyl alcohol
Synonyms	OTF-BYL-6F RARECHEM AL BD 0318 2-FLUORO-6-(TRIFLUOROMETHYL)BENZYL ALCOH 6-fluoro-2-(trifluoromethyl)benzyl alcohol 2-FLUORO-6-(TRIFLUOROMETHYL)BENZYL ALCOHOL 2-fluoro-6-(trifluoromethyl)benzyl alcohol [2-fluoro-6-(trifluoromethyl)phenyl]methanol [2-FLUORO-6-(TRIFLUOROMETHYL)PHENYL]METHANOL
CAS	152211-15-9
InChI	InChI=1/C8H6F4O/c9-7-3-1-2-6(5(7)4-13)8(10,11)12/h1-3,13H,4H2

152211-15-9 - Physico-chemical Properties

Molecular Formula	C8H6F4O
Molar Mass	194.13
Density	1.397g/mLat 25°C(lit.)
Boling Point	180°C(lit.)
Flash Point	>230°F
Vapor Presure	0.462mmHg at 25°C
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	n20/D 1.456(lit.)
MDL	MFCD00061168

152211-15-9 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
Hazard Class	IRRITANT

152211-15-9 - Introduction

2-fluoro-6-(trifluoromethyl)benzyl alcohol is an organic compound with the formula C8H5F4O, containing a fluorine atom and a trifluoromethyl group in its structure. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: colorless or yellowish liquid
-Melting point:-8 ℃
-Boiling point: 170 ℃
-Density: 1.443g/cm³
-Solubility: Soluble in ethanol, ether and chloroform, slightly soluble in water

Use:
- 2-fluoro-6-(trifluoromethyl)benzyl alcohol is an important organic synthesis intermediate, commonly used in drug synthesis and chemical research. It has high chemical stability and biological activity, and can be used as a raw material for the synthesis of drugs and other organic compounds.

Method:
- 2-fluoro-6-(trifluoromethyl)benzyl alcohol can be prepared by the following steps:
1.2-fluorine -6-chlorobenzyl alcohol reacts with trifluoromethyl aluminum iodide in an inert solvent to generate 2-fluorine -6-(trifluoromethyl) anisole.
2.2-fluoro-6-(trifluoromethyl) anisole is reacted with an alkaline agent, such as sodium hydroxide or potassium hydroxide, to obtain 2-fluoro-6-(trifluoromethyl) benzene alcohol.

Safety Information:
- 2-fluoro-6-(trifluoromethyl)benzyl alcohol has certain toxicity and should be used in accordance with safe operation procedures.
-Contact with skin may cause irritation and allergic reactions. Direct contact with skin should be avoided.
-Inhalation or ingestion may be a health hazard and should be avoided.
-When using, storing and handling the compound, observe local safety regulations and take appropriate personal protective measures, such as wearing gloves, goggles and protective masks.

Last Update：2024-04-09 02:00:42