1542135-76-1
LML-134
CAS: 1542135-76-1
Molecular Formula: C19H29N5O3
1542135-76-1 - Names and Identifiers
| Name | LML-134 |
| Synonyms | LML134 LML-134 1-Piperazinecarboxylic acid, 4-cyclobutyl-, 1-(1,6-dihydro-1-methyl-6-oxo-3-pyridazinyl)-4-piperidinyl ester |
| CAS | 1542135-76-1 |
1542135-76-1 - Physico-chemical Properties
| Molecular Formula | C19H29N5O3 |
| Molar Mass | 375.47 |
| Density | 1.37±0.1 g/cm3(Predicted) |
| Boling Point | 509.1±60.0 °C(Predicted) |
| pKa | 7.49±0.70(Predicted) |
| Storage Condition | -20℃ |
1542135-76-1 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.663 ml | 13.317 ml | 26.633 ml |
| 5 mM | 0.533 ml | 2.663 ml | 5.327 ml |
| 10 mM | 0.266 ml | 1.332 ml | 2.663 ml |
| 5 mM | 0.053 ml | 0.266 ml | 0.533 ml |
Last Update：2024-01-02 23:10:35
1542135-76-1 - Reference Information
| Use | LML134 (compound 18b) is an orally active, highly selective H3R (histamine 3 receptor) inverse agonists, the Kis for hH3R cAMP and bdg are 0.3 nM and 12 nM, respectively. LML134 rapidly penetrates the brain, resulting in high H3R occupancy, and detaches its target with rapid kinetic features. LML134 has potential for excessive sleep disorders. |
Last Update：2024-04-09 21:32:00
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CAS: 1542135-76-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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CAS: 1542135-76-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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