155849-49-3

155849-49-3 - Names and Identifiers

Name	4-(TRIFLUOROMETHYL)PIPERIDINE HYDROCHLORIDE
Synonyms	)piperidine hydrochL 4-(TRIFLUOROMETHYL)PIPERIDINE HCL 4-(trifluoromethyl)piperidin-1-ium 4-(TRIFLUOROMETHYL)PIPERIDINE HYDROCHLORIDE
CAS	155849-49-3
EINECS	625-412-3
InChI	InChI=1/C6H10F3N.ClH/c7-6(8,9)5-1-3-10-4-2-5;/h5,10H,1-4H2;1H

155849-49-3 - Physico-chemical Properties

Molecular Formula	C6H11ClF3N
Molar Mass	189.61
Melting Point	155-159°C
Boling Point	134℃
BRN	1341222
Storage Condition	2-8°C
MDL	MFCD04971993
Physical and Chemical Properties	WGK Germany:3

155849-49-3 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany	3
Hazard Note	Irritant
Hazard Class	IRRITANT, IRRITANT-H

155849-49-3 - Introduction

4-(TRIFLUOROMETHYL)PIPERIDINE HYDROCHLORIDE is an organic compound with the chemical formula C9H11F3N · HCl. The following is a description of the properties, uses, preparation and safety information of the compound:

1. Nature:
- 4-(TRIFLUOROMETHYL)PIPERIDINE HYDROCHLORIDE is a solid, usually white crystalline.
-It has a certain solubility and can be dissolved in water and organic solvents.
-Stable at room temperature, but need to avoid moisture.

2. Use:
- 4-(TRIFLUOROMETHYL)PIPERIDINE HYDROCHLORIDE is commonly used as a reaction reagent in organic synthesis.
-It can be used to catalyze hydrogenation reaction, fluorination reaction, amination reaction, etc.
-Due to its high drug potency, this compound is also commonly used in the field of pharmaceutical research.

3. Preparation method:
The preparation of -4-(TRIFLUOROMETHYL)PIPERIDINE HYDROCHLORIDE is often accomplished by reacting 4-(TRIFLUOROMETHYL)PIPERIDINE with hydrochloric acid.
-First, add hydrochloric acid to the organic solvent, and then slowly add 4-(trifluoromethyl) piperidine dropwise. Gas will be generated during the reaction, so it is necessary to pay attention to ventilation.
-When the reaction is completed, the pure 4-(TRIFLUOROMETHYL)PIPERIDINE HYDROCHLORIDE product can be obtained from the reaction solution by crystallization, vacuum drying, etc.

4. Safety Information:
- 4-(TRIFLUOROMETHYL)PIPERIDINE HYDROCHLORIDE is not significantly toxic to humans at lower concentrations under normal circumstances.
-Follow laboratory safety regulations, wear appropriate protective equipment, and avoid contact with skin and eyes.
-Avoid contact with air and moisture during storage, and keep it in a dry, sealed container to avoid the formation of dust or vapor.

Last Update：2024-04-09 21:01:54