156-57-0
2-Aminoethanethiol hydrochloride
CAS: 156-57-0
Molecular Formula: C2H8ClNS
156-57-0 - Names and Identifiers
| Name | 2-Aminoethanethiol hydrochloride |
| Synonyms | H-Cys-NH2·HCl CYSTEAMINE HCL Cysteamine HCL DECARBOXYCYSTEINE HCL CYSTEAMINIUM CHLORIDE Cysteamine hydrochloride CYSTEAMINE HYDROCHLORIDE mercaptamine hydrochloride Mercaptamine hydrochloride Aminoethanethiol hydrochloride mercaptoethylammonium chloride DECARBOXYCYSTEINE HYDROCHLORIDE 2-Aminoethanethiol hydrochloride BETA-MERCAPTOETHYLAMINE HYDROCHLORIDE |
| CAS | 156-57-0 |
| EINECS | 205-858-1 |
| InChI | InChI=1/C2H7NS.ClH/c1-2-3-4;/h3-4H,2H2,1H3;1H |
| InChIKey | OGMADIBCHLQMIP-UHFFFAOYSA-N |
156-57-0 - Physico-chemical Properties
| Molecular Formula | C2H8ClNS |
| Molar Mass | 113.61 |
| Density | 0.75 |
| Melting Point | 67-71°C |
| Boling Point | 238.5℃[at 101 325 Pa] |
| Flash Point | 24.2°C |
| Water Solubility | VERY SOLUBLE |
| Solubility | H2O: 1m at20°C, clear, colorless |
| Vapor Presure | 5.333Pa at 25℃ |
| Appearance | White crystal |
| Color | White |
| Maximum wavelength(λmax) | ['λ: 280 nm Amax: ≤0.3'] |
| Merck | 14,2779 |
| BRN | 3590083 |
| PH | 3.3-5.0 (400g/l, H2O, 20℃) |
| Storage Condition | 2-8°C |
| Stability | Stable, but hygroscopic. Incompatible with strong oxidizing agents. |
| Sensitive | Hygroscopic |
| Refractive Index | 1.6100 (estimate) |
| MDL | MFCD00012904 |
| Physical and Chemical Properties | White crystalline material; Special odor; Easy to deliquescence, soluble in water and ethanol; Unstable to light, the aqueous solution is easy to oxidize to ammonia, sometimes produce precipitation; mp is 71 ℃;LD50 (rat, intraperitoneal) 231.9 mg/kg. |
| Use | Is the manufacture of cimetidine, ranitidine and other drugs intermediates |
156-57-0 - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| UN IDs | UN 3335 |
| WGK Germany | 3 |
| RTECS | KJ0200000 |
| FLUKA BRAND F CODES | 1-3-10-13 |
| TSCA | Yes |
| HS Code | 29309070 |
| Toxicity | LD50 orally in Rabbit: 642 mg/kg |
156-57-0 - Upstream Downstream Industry
156-57-0 - Introduction
Non-flammable and explosive products, with a specific gravity of 1.3-1-4, slightly smelly, easy to deliquesce, green when exposed to iron, and can react with many organic substances. It is a chromium mixture for many metal ions.
Last Update：2022-10-16 17:14:09
156-57-0 - Reference Information
| LogP | -2.14 at 25℃ |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| use | food industry is used as sour agent, color retention agent, preservative, emulsion stabilizer for egg yolk, etc., and is also used in pharmacy. The intermediate of ranitidine and cimetidine can also be used as an antidote for paracetamol poisoning. It is an intermediate for the manufacture of cimetidine, ranitidine and other drugs. Biochemical reagents, complexing agents for heavy metal ions, etc. An aminothiol that can reduce oxidation of important disulfide molecules such as cystine to generate cysteine. Mercaptoethylamine is widely used in applications such as regulating gene expression, consumption of biological hormone inhibin, and coating of nanoparticles, etc.; used for volumetric analysis titration of cobalt, nickel, copper, zinc, cadmium and mercury Used for biochemical research, prevention and treatment of radiation sickness. Cysteamine hydrochloride is used as an antioxidant and as radiation therapy. |
| production method | 2-aminoethanol is used as raw material, brominated with hydrobromic acid, then cyclized with sulfuric acid and carbon disulfide, and finally hydrolyzed with hydrochloric acid. |
Last Update：2024-04-09 15:16:48
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Raw Materials for 156-57-0