156270-06-3
1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic acid
CAS: 156270-06-3
Molecular Formula: C8H6N2O2
156270-06-3 - Names and Identifiers
156270-06-3 - Physico-chemical Properties
| Molecular Formula | C8H6N2O2 |
| Molar Mass | 162.15 |
| Density | 1.49±0.1 g/cm3(Predicted) |
| Melting Point | 205-209 °C |
| Boling Point | 425.3±45.0 °C(Predicted) |
| Flash Point | 224.03°C |
| Water Solubility | Slightly soluble in water. |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | Solid |
| pKa | 0.52±0.20(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.743 |
| MDL | MFCD07778360 |
156270-06-3 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| HS Code | 29339980 |
| Hazard Class | IRRITANT |
156270-06-3 - Introduction
1H-Pyrrolo [2,3-b] Pyridine-3-Carboxylic acid is an organic compound with the chemical formula C12H8N2O2.
Nature:
1H-Pyrrolo [2,3-b] Pyridine-3-Carboxylic acid is a solid with a white crystalline form. It is a weak acid that can react with a base to form the corresponding salt. The compound is insoluble in water at normal temperature, but soluble in organic solvents such as chloroform, methanol and ethanol.
Use:
1H-Pyrrolo [2,3-b] Pyridine-3-Carboxylic acid is widely used as an intermediate in organic synthesis in the fields of medicine, pesticide and dye. It can be used for the synthesis of aminopyrimidine anticancer drugs, trifluoro chloropyrimidine and other drugs.
Method:
1H-Pyrrolo [2,3-b] Pyridine-3-Carboxylic acid has many preparation methods. A common method is through benzopyrrolo [2,3-b] pyridine-3, the 6-diketone is obtained by reaction with formic acid. Specific preparation methods can be found in the literature and chemical handbooks, as required.
Safety Information:
1h-yrrolo [2,3-b] The safety of Pyridine-3-Carboxylic acid is good, but necessary safety protection measures are still needed. Rinse immediately with water when in contact with skin. Wear chemical protective gloves and eye protection equipment when handling this compound. Avoid inhaling its dust or contact with food and drinking water. If necessary, it should be operated in a well-ventilated area to prevent its vapor concentration from exceeding safety standards. When using and storing the compound, it should be handled in accordance with relevant regulations and safe operating procedures.
Nature:
1H-Pyrrolo [2,3-b] Pyridine-3-Carboxylic acid is a solid with a white crystalline form. It is a weak acid that can react with a base to form the corresponding salt. The compound is insoluble in water at normal temperature, but soluble in organic solvents such as chloroform, methanol and ethanol.
Use:
1H-Pyrrolo [2,3-b] Pyridine-3-Carboxylic acid is widely used as an intermediate in organic synthesis in the fields of medicine, pesticide and dye. It can be used for the synthesis of aminopyrimidine anticancer drugs, trifluoro chloropyrimidine and other drugs.
Method:
1H-Pyrrolo [2,3-b] Pyridine-3-Carboxylic acid has many preparation methods. A common method is through benzopyrrolo [2,3-b] pyridine-3, the 6-diketone is obtained by reaction with formic acid. Specific preparation methods can be found in the literature and chemical handbooks, as required.
Safety Information:
1h-yrrolo [2,3-b] The safety of Pyridine-3-Carboxylic acid is good, but necessary safety protection measures are still needed. Rinse immediately with water when in contact with skin. Wear chemical protective gloves and eye protection equipment when handling this compound. Avoid inhaling its dust or contact with food and drinking water. If necessary, it should be operated in a well-ventilated area to prevent its vapor concentration from exceeding safety standards. When using and storing the compound, it should be handled in accordance with relevant regulations and safe operating procedures.
Last Update：2024-04-09 02:00:42
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Product Name: 1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid Visit Supplier Webpage Request for quotation
CAS: 156270-06-3
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CAS: 156270-06-3
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View History
156270-06-3
164081-25-8
二氟甲基苯砜
134021-15-1
3-(N-ACETYL-N-ETHYLAMINO)PYRROLIDINE
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164081-25-8
二氟甲基苯砜
134021-15-1
3-(N-ACETYL-N-ETHYLAMINO)PYRROLIDINE
六氟锑酸亚硝
Bis(4-fluorobenzyl)amine
1074-41-5
2-(2,5-dichlorophenyl)ethanamine