1566-81-0
NS1652
CAS: 1566-81-0
Molecular Formula: C15H11F3N2O3
1566-81-0 - Names and Identifiers
| Name | NS1652 |
| Synonyms | NS1652 2-(3-(3-(Trifluoromethyl)phenyl)ureido)benzoic acid Benzoic acid, 2-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]- |
| CAS | 1566-81-0 |
1566-81-0 - Physico-chemical Properties
| Molecular Formula | C15H11F3N2O3 |
| Molar Mass | 324.25 |
| Density | 1.501±0.06 g/cm3(Predicted) |
| Melting Point | 169-171 °C |
| Boling Point | 355.9±42.0 °C(Predicted) |
| pKa | 3.51±0.36(Predicted) |
| Storage Condition | Room Temprature |
| In vitro study | NS1652 potently inhibits the chloride conductance (IC 50 , 1.6 μM) in human and mouse red blood cells, but only weakly inhibits VRAC (IC 50 , 125 μM) in HEK293 cells. NS1652 markedly blocks the NO production with an IC 50 of 3.1 μM in BV2 cells. NS1652 also down-regulates iNOS expression at 3 μM, and completely abolishes at 10 μM in BV2 cells. NS1652 (0, 1.0, 3.3, 10, and 20 μM) causes increasing hyperpolarization due to inhibition of the chloride conductance in normal erythrocytes. NS1652 lowers the net KCl loss from deoxygenated sickle cells from about 12 mM cells/h to about 4 mM cells/h. NS1652 (20 μM) completely and reversiblely inhibits the red cell Cl - conductance. |
| In vivo study | NS1652 (50 mg/kg, i.v.) blocks murine erythrocyte Cl - conductance by >90% in mice. |
1566-81-0 - Introduction
NS1652 is a compound whose chemical name is N-phenyl -4-dimethylamino styrene sulfamide. The following is a description of the nature, use, preparation and safety information of NS1652:
Nature:
-Appearance: NS1652 is a white crystalline or powdery solid.
-Solubility: Good solubility in common organic solvents.
-Melting point: The melting point of NS1652 is about 165-170°C.
Use:
- NS1652 is often used as an organic synthesis intermediate, can be used for the preparation of fluorescent dyes, polymer materials.
-Due to its good solubility and stability, NS1652 can also be used in the preparation of dye-sensitized solar cells, organic light-emitting diodes (OLED) and other optoelectronic devices.
Preparation Method:
-The preparation method of NS1652 is more complicated and is usually obtained through multi-step synthesis.
-A common preparation method is to synthesize n-phenyl-4-dimethylaminobenzaldehyde from benzene, and then react it with sulfuryl chloride to produce the final product ns1652.
Safety Information:
- NS1652 is a chemical, and personal protective measures should be taken when using it, such as wearing protective glasses and gloves.
-When conducting experiments or operations, avoid inhaling its dust or touching its skin.
- NS1652 is an organic compound with certain toxicity and irritation. It is recommended to use in a well-ventilated laboratory environment.
-During handling and storage, relevant safety procedures should be followed and stored properly to prevent reaction with incompatible materials.
Please note that the above information is for reference only. The specific nature, use, method and safety information need to be confirmed by referring to relevant literature or consulting professionals.
Nature:
-Appearance: NS1652 is a white crystalline or powdery solid.
-Solubility: Good solubility in common organic solvents.
-Melting point: The melting point of NS1652 is about 165-170°C.
Use:
- NS1652 is often used as an organic synthesis intermediate, can be used for the preparation of fluorescent dyes, polymer materials.
-Due to its good solubility and stability, NS1652 can also be used in the preparation of dye-sensitized solar cells, organic light-emitting diodes (OLED) and other optoelectronic devices.
Preparation Method:
-The preparation method of NS1652 is more complicated and is usually obtained through multi-step synthesis.
-A common preparation method is to synthesize n-phenyl-4-dimethylaminobenzaldehyde from benzene, and then react it with sulfuryl chloride to produce the final product ns1652.
Safety Information:
- NS1652 is a chemical, and personal protective measures should be taken when using it, such as wearing protective glasses and gloves.
-When conducting experiments or operations, avoid inhaling its dust or touching its skin.
- NS1652 is an organic compound with certain toxicity and irritation. It is recommended to use in a well-ventilated laboratory environment.
-During handling and storage, relevant safety procedures should be followed and stored properly to prevent reaction with incompatible materials.
Please note that the above information is for reference only. The specific nature, use, method and safety information need to be confirmed by referring to relevant literature or consulting professionals.
Last Update：2024-04-09 21:04:16
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Product Name: NS1652 Visit Supplier Webpage Request for quotation
CAS: 1566-81-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 1566-81-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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