157649-56-4

157649-56-4 - Names and Identifiers

Name	Methyl5-nitro-1H-indole-2-carboxylate
Synonyms	5-NITRO-2-INDOLECARBOXYLIC ACID Methyl5-nitro-1H-indole-2-carboxylate 1H-Indole-2-carboxylic acid, 5-nitro-, Methyl ester
CAS	157649-56-4

157649-56-4 - Physico-chemical Properties

Molecular Formula	C10H8N2O4
Molar Mass	220.19
Density	1.452±0.06 g/cm3(Predicted)
Boling Point	424.2±25.0 °C(Predicted)
pKa	13.22±0.30(Predicted)
Storage Condition	2-8°C

157649-56-4 - Introduction

Methyl5-nitro-1H-indole-2-carboxylate is an organic compound with the chemical formula C11H8N2O4.

It is a yellow to orange crystal with a high melting point and boiling point. It has low solubility and is hardly soluble in water, but is easily soluble in common organic solvents such as ethanol, acetone and dichloromethane.

Methyl5-nitro-1H-indole-2-carboxylate is commonly used as an intermediate in organic synthesis and can be used to prepare indole compounds. Especially in the field of drug synthesis, it is often used as a starting material for the preparation of a variety of anti-tumor and anti-viral compounds.

There are various methods for preparing Methyl5-nitro-1H-indole-2-carboxylate, and commonly used methods include the oxidation of indole derivatives and methyl picolinate. Among them, the method of oxidizing indole derivatives can be obtained by reacting indole with nitric acid to obtain 5-nitro-1H-indole, and then reacting with methyl formate to produce the target product.

Regarding safety information, Methyl5-nitro-1H-indole-2-carboxylate are organic compounds and have certain risks. Contact with or inhalation of its dust or gas may be harmful to health, care should be taken to avoid contact with skin, eyes and respiratory tract. During handling and storage, appropriate safety measures should be taken, such as wearing protective gloves and glasses, and maintaining good ventilation conditions. Such as accidental or a large number of contact, should be timely medical treatment. Refer to the relevant safety data sheet for detailed safety information.

Last Update：2024-04-09 20:02:46