160434-48-0

Name	4-DesMethyl Istradefylline
Synonyms	Itraphylline impurities869 Istradefylline Impurity 14 4-DesMethyl Istradefylline Istradefylline M1 metabolite 4-DesMethyl Istradefylline impurity Istradefylline 4-O-Desmethyl Impurity (E)-1,3-diethyl-8-(4-hydroxy-3-methoxystyryl)-7-methyl-1H-purine-2,6(3H,7H)-dione 1H-Purine-2,6-dione, 1,3-diethyl-3,7-dihydro-8-[2-(4-hydroxy-3-methoxyphenyl)ethenyl]-7-methyl-, (E)- (9CI)
CAS	160434-48-0

Molecular Formula	C19H22N4O4
Molar Mass	370.40238

biological activity	4-desmethyllline is a metabolite of isafilline. Isafilline is a potent, selective, orally available adenosine A2A receptor antagonist with a Ki value of 2.2 nM in the Parkinson disease model test.
Use	4-desmethyllline is an importance of istradeylline (I927000), a selective A(2A) angionist used in the treatment of Parkinson's disease. 4-Desmethyl istradefylline have also been shown to exh The lbit inhibitory potency towards adenosine A2A receptors and is classified as its an adenosine A2A receptor antagonist.

Last Update：2024-04-09 21:48:26

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