Molecular Formula | C24H38N2O10 |
Molar Mass | 514.57 |
Storage Condition | 2-8°C,干燥,密封 |
MDL | MFCD28118912 |
In vitro study | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
biological activity | TCO-PEG4-NHS ester is a PROTAC Bridge belonging to the PEG class. TCO-PEG4-NHS ester can be used to synthesize a range of PROTAC molecules. TCO-PEG4-NHS ester is a cleavable ADC attachment Bridge used in the synthesis of antibody drug conjugates (ADCs). |