16135-36-7

16135-36-7 - Names and Identifiers

Name	Methyl 4-aminopyridine-3-carboxylate
Synonyms	RARECHEM AL BF 1386 METHYL-4-AMINONICOTINATE 4-AMINONICOTINIC ACID METHYL ESTER Methyl 4-aminopyridine-3-carboxylate 4-Amino-nicotinic acid methyl ester methyl 4-aminopyridine-3-carboxylate 4-amino-3-pyridinecarboxylic acid methyl ester 4-AMINOPYRIDINE-3-CARBOXYLIC ACID METHYL ESTER Methyl 4-aminopyridine-3-carboxylate, 4-Aminonicotinic acid methyl ester
CAS	16135-36-7
InChI	InChI=1/C7H8N2O2/c1-11-7(10)5-4-9-3-2-6(5)8/h2-4H,1H3,(H2,8,9)

16135-36-7 - Physico-chemical Properties

Molecular Formula	C7H8N2O2
Molar Mass	152.15
Density	1.238±0.06 g/cm3(Predicted)
Melting Point	172-174℃
Boling Point	288.7±20.0 °C(Predicted)
Flash Point	128.4°C
Vapor Presure	0.0023mmHg at 25°C
Appearance	White powder
pKa	7.04±0.12(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.57
MDL	MFCD00955996

16135-36-7 - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37 - Wear suitable gloves.
UN IDs	UN2811
HS Code	29333990

16135-36-7 - Introduction

Methyl 4-aminopyridine-3-carboxylate (also known as Methyl nitridol) is an organic compound with the chemical formula C6H6N2O2. The following is a description of the nature, use, preparation and safety information of Methyl 4-aminopyridine-3-carboxylate:

Nature:
-Appearance: Methyl 4-aminopyridine-3-carboxylate is a colorless crystalline solid.
-Solubility: It has low solubility in water and is relatively soluble in alcohol and ether solvents.
-Stability: It is a relatively stable compound that can be stored for a long time at room temperature.

Use:
-Pharmaceutical field: Methyl 4-aminopyridine-3-carboxylate is commonly used as a drug intermediate and plays an important role in the synthesis of drugs.
-Vitamin synthesis: It can also be used to synthesize the main ingredients in vitamin B6.
-Photosensitive material: Methyl 4-aminopyridine-3-carboxylate is also used to prepare some photosensitive materials and photosensitive films.

Method:
Methyl 4-aminopyridine-3-carboxylate is generally prepared by aminoalkylation of an intermediate in the synthesis of the diabetes drug insulin. Specific synthetic methods can use Methyl chloroformate to react with aminonicotinic acid under alkaline conditions to produce Methyl 4-aminopyridine-3-carboxylate.

Safety Information:
- Methyl 4-aminopyridine-3-carboxylate is relatively stable, but it still needs to be handled carefully.
-In case of contact with skin, eyes or inhalation of dust, rinse immediately with water and seek medical help.
-When using, pay attention to protective measures, avoid inhaling dust, and avoid contact with skin and eyes.
-When storing, store Methyl 4-aminopyridine-3-carboxylate in a dry, well-ventilated place, away from fire and oxidizing agents.

Last Update：2024-04-09 15:17:53