16183-32-7
N-(4-chlorobenzyl)butan-1-amine
CAS: 16183-32-7
Molecular Formula: C11H16ClN
16183-32-7 - Names and Identifiers
| Name | N-(4-chlorobenzyl)butan-1-amine |
| Synonyms | Aids107180 Aids-107180 AKOS LT-992X0028 UKRORGSYN-BB BBV-125481 2298-58-0 (Hydrochloride) N-(4-CHLOROBENZYL)BUTAN-1-AMINE N-(4-chlorobenzyl)butan-1-amine N-(4-CHLOROPHENYLMETHYL)BUTYLAMINE Benzenemethanamine, N-butyl-4-chloro- benzenemethanamine, N-butyl-4-chloro- |
| CAS | 16183-32-7 |
| InChI | InChI=1/C11H16ClN/c1-2-3-8-13-9-10-4-6-11(12)7-5-10/h4-7,13H,2-3,8-9H2,1H3 |
16183-32-7 - Physico-chemical Properties
| Molecular Formula | C11H16ClN |
| Molar Mass | 197.7 |
| Density | 1.026g/cm3 |
| Boling Point | 264.2°C at 760 mmHg |
| Flash Point | 113.6°C |
| Vapor Presure | 0.00984mmHg at 25°C |
| Refractive Index | 1.516 |
16183-32-7 - Introduction
N-(4-chlorobenzyl)butan-1-amine, also known as 4-chlorobenzyl-butyl Amine, is an organic compound. The following is a detailed description of its nature, use, preparation and safety information:
Nature:
-Appearance: colorless liquid
-Molecular formula: C11H16ClN
-Molecular weight: 199.7g/mol
-Melting point:-20 degrees Celsius
-Boiling point: 263 to 264 degrees Celsius
-Density: 0.994g/cm³
-Solubility: Soluble in organic solvents such as ethanol and dimethyl sulfoxide
Use:
N-(4-chlorobenzyl)butan-1-amine have a wide range of applications in pharmaceutical synthesis and organic synthesis. It can be used as a drug intermediate for the synthesis of anti-tumor, antibiotics and antiviral drugs. In addition, it can also be used in organic synthesis reactions such as amination reaction, hydroxyl protection reaction and aldehyde protection reaction.
Method:
The preparation of N-(4-chlorobenzyl)butan-1-amine is usually accomplished by the following steps:
1. First, 4-chlorobenzyl bromide is reacted with butanol to obtain 4-chlorobenzyl butanol.
2. Next, 4-chlorobenzylbutanol is reacted with a catalyst such as alumina and cuprous chloride to produce N-(4-chlorobenzyl)butan-1-amine. The reaction conditions may be normal temperature or heating.
Safety Information:
- N-(4-chlorobenzyl)butan-1-amine may cause irritation to the eyes, skin and respiratory tract, so care should be taken to avoid contact when using. Wear protective goggles, gloves and respiratory protection if necessary.
-During operation, good ventilation should be ensured. Avoid inhaling its vapors or dust.
-If you come into contact with this compound, rinse the affected area immediately with soap and water and seek medical help.
-Please store N-(4-chlorobenzyl)butan-1-amine in a dry, ventilated and sealed container, away from fire and oxidizing agents.
Please note that the use and operation of any organic compound should follow the safe operation procedures and proceed after understanding and mastering relevant knowledge.
Nature:
-Appearance: colorless liquid
-Molecular formula: C11H16ClN
-Molecular weight: 199.7g/mol
-Melting point:-20 degrees Celsius
-Boiling point: 263 to 264 degrees Celsius
-Density: 0.994g/cm³
-Solubility: Soluble in organic solvents such as ethanol and dimethyl sulfoxide
Use:
N-(4-chlorobenzyl)butan-1-amine have a wide range of applications in pharmaceutical synthesis and organic synthesis. It can be used as a drug intermediate for the synthesis of anti-tumor, antibiotics and antiviral drugs. In addition, it can also be used in organic synthesis reactions such as amination reaction, hydroxyl protection reaction and aldehyde protection reaction.
Method:
The preparation of N-(4-chlorobenzyl)butan-1-amine is usually accomplished by the following steps:
1. First, 4-chlorobenzyl bromide is reacted with butanol to obtain 4-chlorobenzyl butanol.
2. Next, 4-chlorobenzylbutanol is reacted with a catalyst such as alumina and cuprous chloride to produce N-(4-chlorobenzyl)butan-1-amine. The reaction conditions may be normal temperature or heating.
Safety Information:
- N-(4-chlorobenzyl)butan-1-amine may cause irritation to the eyes, skin and respiratory tract, so care should be taken to avoid contact when using. Wear protective goggles, gloves and respiratory protection if necessary.
-During operation, good ventilation should be ensured. Avoid inhaling its vapors or dust.
-If you come into contact with this compound, rinse the affected area immediately with soap and water and seek medical help.
-Please store N-(4-chlorobenzyl)butan-1-amine in a dry, ventilated and sealed container, away from fire and oxidizing agents.
Please note that the use and operation of any organic compound should follow the safe operation procedures and proceed after understanding and mastering relevant knowledge.
Last Update：2024-04-09 21:01:54
