163271-32-7

Name	5-Aminolevulinic acid benzyl ester hydrochloride
Synonyms	ALA BENZYL ESTER HYDROCHLORIDE 5-aminolevulinic acid benzyl ester 5-Aminolevulinic acid benzyl ester HCl Benzyl 5-amino-4-oxopentanoate hydrochloride AMINOLEVULINIC ACID BENZYL ESTER HYDROCHLORIDE 5-Aminolevulinic acid benzyl ester hydrochloride 5-AMINOLEVULINIC ACID BENZYL ESTER HYDROCHLORIDE DELTA-AMINOLEVULINIC ACID BENZYL ESTER HYDROCHLORIDE 5-AMINO-4-OXOPENTANOIC ACID BENZYL ESTER HYDROCHLORIDE
CAS	163271-32-7

Molecular Formula	C12H16ClNO3
Molar Mass	257.71
In vitro study	5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) (0.6-0.12 mM; 3 h) induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines SW480.

biological activity	5-ALA benzyl ester hydrozolide is a protoporphyrin precursor used as a photodetector. 5-ALA benzyl ester hydrochloride induces the accumulation of protoporphyrin IX (PPIX) in colon cancer cell lines.
Animal Model:	Female CBA/Gy mouse (CaNT tumour model)
Dosage:	31 mg/kg
Administration:	i.v. ; 1 hours
Result:	Reducing the dose of 5-ALA benzyl ester hydrochloride resulted in a dose-dependent reduction in the concentration of porphyrins accumulating in the CaNT tumour.

Last Update：2024-04-09 15:16:58