1644-68-4

1644-68-4 - Names and Identifiers

Name	2,3-Bis(trifluoromethyl)pyridine
Synonyms	2,3-Bis(trfluoromethyl)pyridine 2,3-Bis(trifluoromethyl)pyridine 2,3-BIS(TRIFLUOROMETHYL)PYRIDINE Pyridine, 2,3-bis(trifluoromethyl)-
CAS	1644-68-4
EINECS	621-957-6
InChI	InChI=1/C7H3F6N/c8-6(9,10)4-2-1-3-14-5(4)7(11,12)13/h1-3H

1644-68-4 - Physico-chemical Properties

Molecular Formula	C7H3F6N
Molar Mass	215.1
Density	1.498 g/mL at 25 °C
Melting Point	-2°C
Boling Point	85 °C/18 mmHg
Flash Point	159°F
Vapor Presure	9.76mmHg at 25°C
BRN	1622028
pKa	-1.87±0.22(Predicted)
Storage Condition	Room Temprature
Refractive Index	n20/D 1.393
MDL	MFCD03093763

1644-68-4 - Risk and Safety

Risk Codes	R25 - Toxic if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN 2810 6.1/PG 3
WGK Germany	3
Hazard Note	Irritant/Flammable
Hazard Class	6.1
Packing Group	II

1644-68-4 - Introduction

2,3-bis (trifluoromethyl)pyridine is an organic compound with the chemical formula C7H3F6N. The following is a description of its nature, use, preparation and safety information:

Nature:
2,3-bis (trifluoromethyl)pyridine is a colorless liquid with a trifluoromethyl group. It is stable at room temperature, but can burn. The compound has a strong pungent odor. It is insoluble in water, but can be compatible with many organic solvents.

Use:
2,3-bis (trifluoromethyl)pyridine is mainly used as an intermediate in drugs and pesticides. It can be used as a precursor for the synthesis of important drugs such as antibiotics, anti-inflammatory drugs, pesticides and herbicides. In addition, it can also be used in metal surface treatment, high-energy coating, rubber processing and liquid crystal displays.

Method:
The preparation of 2,3-bis (trifluoromethyl)pyridine is usually obtained by reacting 2,3-diaminopyridine with trimethyl trifluoroformate. In the reaction, the reactant mixture is heated in an appropriate solvent to form the product, which is then isolated and purified.

Safety Information:
When handling 2,3-bis (trifluoromethyl)pyridine, the following safety precautions should be paid attention to: When coming into contact with this compound, direct contact with skin, eyes and respiratory tract should be avoided. Wear appropriate protective gloves, glasses and masks during operation. It has low volatility, so it should be operated in a well-ventilated place to avoid inhaling its vapors. In addition, when storing and handling, the relevant safety regulations for chemical storage and waste disposal should be followed.

Last Update：2024-04-09 20:52:54