167678-46-8 - Names and Identifiers
167678-46-8 - Physico-chemical Properties
Molecular Formula | C10H9ClO3
|
Molar Mass | 212.63 |
Density | 1,25 g/cm3 |
Melting Point | 31-35°C |
Boling Point | 148°C/11mmHg(lit.) |
Flash Point | 123.6°C |
Solubility | Chloroform, Dichloromethane |
Vapor Presure | 0.00151mmHg at 25°C |
Appearance | Oil |
Color | Light Yellow |
BRN | 8054543 |
Storage Condition | Room Temprature |
Sensitive | Moisture Sensitive |
Refractive Index | 1.532 |
MDL | MFCD02094037 |
167678-46-8 - Risk and Safety
Risk Codes | R34 - Causes burns
R43 - May cause sensitization by skin contact
R35 - Causes severe burns
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S7/8 -
|
UN IDs | 3261 |
HS Code | 29159000 |
Hazard Class | 8 |
Packing Group | III |
167678-46-8 - Introduction
Chloride, also known as ketone Chloride, its chemical formula is C10H9ClO2. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: Colorless to light yellow liquid
-Molecular weight: 188.63g/mol
-Melting point:-6 ° C
-Boiling point: 226-228 ° C
-Density: 1.281 g/mL
-Solubility: Soluble in organic solvents such as ether and chloroform, almost insoluble in water
-Chemical properties: It is a kind of acid chloride, which has the chemical reactivity of common acid chloride. It can be condensed with amines, alcohols, etc. to generate corresponding amides or esters. In the air susceptible to moisture and the role of hydrochloric acid gas, the formation of the corresponding keto acid.
Use:
-, chloroide is widely used in organic synthesis as an acylating agent and a gradient protector.
-It can be used as an intermediate for the synthesis of organic chemicals such as drugs, pesticides, dyes, spices, etc.
-In the field of medicine, Chloride can be used in the preparation of non-steroidal anti-inflammatory drugs and other drugs.
Method:
Chloride can be prepared by one of the following methods:
-Acylation reaction: 2-methyl -3-acetophenol is reacted with benzoic acid and thionyl chloride to obtain the product.
-transketonation: The product is generated by the reaction of 2-methyl -3-acetophenol with substituted ketone and tert-butanone peroxide.
Safety Information:
-etc. Chloride is an irritant substance and should be avoided in contact with the skin, eyes and respiratory tract.
-use should wear protective glasses and gloves, to ensure good ventilation.
-In case of accidental contact, rinse immediately with plenty of water and seek medical help.
-Should be stored in a cool, dry place, away from fire and combustibles.
Last Update:2024-04-09 15:17:53