170729-79-0
[2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine
CAS: 170729-79-0
Molecular Formula: C20H18F7NO2
170729-79-0 - Names and Identifiers
| Name | [2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine |
| Synonyms | (2r-(2ar Fosaprepitant Impurity 32 (S,R,S)-Enantiomer Aprepitant Aprepitant M2 Metabolite (1S, 2R, 3S)-Isomer [2R-[2α(S*),3α]]-2-[1-[3,5-bis(trifluoromethyl)phenyl] (2R,3S)-2-{(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}-3-(4-fluorophenyl)morpholine [2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine Morpholine,2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-[2R-[2a(S*),3a]] [2R-[2α(S*),3α]]-2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)- Morpholine |
| CAS | 170729-79-0 |
| InChI | InChI=1/C20H18F7NO2/c1-11(13-8-14(19(22,23)24)10-15(9-13)20(25,26)27)30-18-17(28-6-7-29-18)12-2-4-16(21)5-3-12/h2-5,8-11,17-18,28H,6-7H2,1H3/t11-,17-,18+/m0/s1 |
170729-79-0 - Physico-chemical Properties
| Molecular Formula | C20H18F7NO2 |
| Molar Mass | 437.35 |
| Density | 1.37 |
| Boling Point | 387.9±42.0 °C(Predicted) |
| Flash Point | 188.4°C |
| Vapor Presure | 3.2E-06mmHg at 25°C |
| pKa | 6.93±0.60(Predicted) |
| Refractive Index | 1.504 |
170729-79-0 - Introduction
[2R-[2aR *),3a]-2-[1-[3,5-bis (trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-chemical formula: C20H19F5NO2
-Molecular weight: 409.36g/mol
-Appearance: White or off-white crystalline powder
-Melting point: about 95-98 ° C
-Boiling point: 446.1 ° C
Use:
- [2R-[2aR *),3a]-2-[1-[3,5-bis (trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine is a pharmaceutical intermediate used in chemical synthesis to prepare other organic compounds or drugs.
Method:
[2R-[2aR *),3a]-2-[1-[3,5-bis (trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl) the preparation method of morpholine may be confidential information protected by patents, so specific details cannot be provided. In general, it can be synthesized by a chemical reaction, including a substitution reaction in an organic synthesis method, an esterification reaction, and the like.
Safety Information:
-Follow personal protective measures when using, including wearing appropriate protective glasses and gloves, and ensure that you operate in a well-ventilated environment.
-This compound may cause irritation to the eyes, skin and respiratory tract. Avoid direct contact.
-Please store in a sealed container, away from heat and fire. Avoid contact with oxidizing agents and strong acids.
-When using or disposing, please comply with local laws and regulations.
Please note that the above information is for reference only. The specific synthesis method and safe operation should be determined according to the actual situation and the specific nature of the chemical. Correct laboratory practices and safe operating guidelines should be followed when handling chemicals.
Nature:
-chemical formula: C20H19F5NO2
-Molecular weight: 409.36g/mol
-Appearance: White or off-white crystalline powder
-Melting point: about 95-98 ° C
-Boiling point: 446.1 ° C
Use:
- [2R-[2aR *),3a]-2-[1-[3,5-bis (trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine is a pharmaceutical intermediate used in chemical synthesis to prepare other organic compounds or drugs.
Method:
[2R-[2aR *),3a]-2-[1-[3,5-bis (trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl) the preparation method of morpholine may be confidential information protected by patents, so specific details cannot be provided. In general, it can be synthesized by a chemical reaction, including a substitution reaction in an organic synthesis method, an esterification reaction, and the like.
Safety Information:
-Follow personal protective measures when using, including wearing appropriate protective glasses and gloves, and ensure that you operate in a well-ventilated environment.
-This compound may cause irritation to the eyes, skin and respiratory tract. Avoid direct contact.
-Please store in a sealed container, away from heat and fire. Avoid contact with oxidizing agents and strong acids.
-When using or disposing, please comply with local laws and regulations.
Please note that the above information is for reference only. The specific synthesis method and safe operation should be determined according to the actual situation and the specific nature of the chemical. Correct laboratory practices and safe operating guidelines should be followed when handling chemicals.
Last Update：2024-04-09 15:17:53
