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17090-79-8

Monensin

CAS: 17090-79-8

Molecular Formula: C36H62O11

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17090-79-8 - Names and Identifiers

Name Monensin
Synonyms a3823a
monelan
Monensin
elancoban
Monensin A
Monensine sodium
gamma,2,8-tetramethyl--furyl)-2-furyl)-9-hydroxy-beta-methoxy-alph
2-(5-ethyltetrahydro-5-(tetrahydro-3-6-dioxaspiro(4.5)decane-7-butyricacid
4-[2-[2-Ethyl-5-(6-hydroxy-6-hydroxymethyl-3,5-dimethyltetrahydropyran-2-yl)-3-methyloctahydro-[2,2]bifuranyl-5-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]-3-methoxy-2-methylpentanoic acid
4-(2-{2-Ethyl-5'-[6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-3'-methyloctahydro-2,2'-bifuran-5-yl}-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl)-3-methoxy-2-methylpentanoate
1,6-dioxaspiro[4.5]decane-7-butanoato, 2-[2-ethyloctahydro-3'-methyl-5'-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl][2,2'-bifuran]-5-yl]-9-hydroxy-beta-methoxy-alpha,gamma,2,8-tetramethyl-, ion(1-)
sodium (2S,3R,4R)-4-[(2S,7S,8R,9S)-2-[(2R,5S)-5-ethyl-5-[(3S,5R)-5-[(3S,5R,6S)-6-ethyl-6-hydroxy-3,5-dimethyl-tetrahydropyran-2-yl]-3-methyl-tetrahydrofuran-2-yl]tetrahydrofuran-2-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl]-3-methoxy-2-methyl-pentanoate
(2S,3R,4S)-4-[(2S,5R,7S,8R,9S)-2-{(2S,2'R,3'S,5R,5'R)-2-ethyl-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-3'-methyloctahydro-2,2'-bifuran-5-yl}-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]-3-methoxy-2-methylpentanoic acid
(2R,3S,4R)-4-[(2R,5R,7S,8R,9S)-2-{(2S,2'S,3'R,5R,5'S)-2-ethyl-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-3'-methyloctahydro-2,2'-bifuran-5-yl}-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]-3-methoxy-2-methylpentanoic acid
CAS 17090-79-8
EINECS 241-154-0
InChI InChI=1/C37H64O10.Na/c1-11-35(32-21(4)18-27(43-32)29-20(3)17-22(5)37(41,12-2)46-29)14-13-28(44-35)34(9)15-16-36(47-34)19-26(38)23(6)31(45-36)24(7)30(42-10)25(8)33(39)40;/h20-32,38,41H,11-19H2,1-10H3,(H,39,40);/q;+1/p-1/t20-,21-,22+,23+,24+,25-,26-,27+,28+,29?,30+,31-,32?,34-,35-,36?,37-;/m0./s1

17090-79-8 - Physico-chemical Properties

Molecular FormulaC36H62O11
Molar Mass670.87
Density1.0773 (rough estimate)
Melting Point103-105°C
Boling Point608.24°C (rough estimate)
Specific Rotation(α)D +47.7°
Flash Point219.3°C
Vapor Presure1.85E-25mmHg at 25°C
pKa6.6 (in 66% DMF)
Storage Condition2-8°C
Refractive Index1.5465 (estimate)

17090-79-8 - Risk and Safety

Hazard SymbolsT - Toxic
Toxic
Risk Codes25 - Toxic if swallowed
Safety DescriptionS36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDsUN 3462 6.1/PG 2
WGK Germany3
RTECSJH2830000
Hazard Class6.1(a)
Packing GroupII
ToxicityLD50 of monensin complex in mice, chicks (mg/kg): 43.8 ± 5.2, 284 ± 47 orally (Haney, Hoehn)

17090-79-8 - Nature

Open Data Verified Data

yellow-brown or off-white powder.

Last Update：2024-01-02 23:10:35

17090-79-8 - Preparation Method

Open Data Verified Data

prepared by fermentation of Streptomyces cinnamomi.

Last Update：2022-01-01 10:11:03

17090-79-8 - Use

Open Data Verified Data

used as an anticoccidial drug. For the control and prevention of chicken, lamb and calf coccidiosis, promote the growth of cattle and sheep.

Last Update：2022-01-01 10:11:04

17090-79-8 - Reference Information

EPA chemical information Information provided by: ofmpub.epa.gov (external link)
overview monensin can hardly be absorbed in the digestive tract, so there is generally no problem of residue in tissues and transfer to edible livestock products. The application of monensin during high-precision fattening can increase the production of propionic acid, reduce the degradation of protein in the rumen in the feed, and increase the total amount of rumen protein, increase the utilization rate of net energy and nitrogen, and make The intestinal wall becomes thinner and is conducive to the penetration and absorption of nutrients. The total amount of ciliates and bacteria in the rumen increases by 1 to 2 times, and also stimulates the pituitary gland to secrete hormones to promote growth and development, so as to improve the weight gain rate and feed conversion rate.
Uses Monensin, also known as monomycin or rumen, is a feed additive widely used in ruminants. It was originally produced by Streptomyces A polyether antibiotic that can control the proportion of volatile fatty acids in the rumen, reduce protein degradation in the rumen, and reduce feed dry matter consumption, improve the utilization rate of nutrients and improve the utilization rate of animal energy.
Biological activity Monensin is a fat-soluble natural biologically active ionophore produced by Streptomyces, which can bind protons and monovalent cations. Monensin has broad-spectrum activity against human opportunistic pathogens in both drug-sensitive and drug-resistant strains. Monensin can induce apoptosis of various cancer cell lines.
toxic substance data information provided by: pubchem.ncbi.nlm.nih.gov (external link)
Last Update：2024-04-09 19:05:07
17090-79-8
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Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: Monensin Request for quotation
CAS: 17090-79-8
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 0086 189 4982 3763
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17090-79-8
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