171364-85-5

171364-85-5 - Names and Identifiers

Name	QUINOLINE-3-BORONIC ACID PINACOLATE
Synonyms	AKOS BRN-1143 QUINOLINE-3-BORONIC ACID PINACOLATE quinoline-boronic acid pinacol ester QUINOLINE-3-BORONIC ACID PINACOL ESTER Quinoline-3-boronic acid, pinacol ester 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)QUINOLINE Quinoline, 3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)- 3-hydroxy-2,3-diMethylbutan-2-yl hydrogen quinolin-3-ylboronate
CAS	171364-85-5
InChI	InChI=1/C15H18BNO2/c1-14(2)15(3,4)19-16(18-14)12-9-11-7-5-6-8-13(11)17-10-12/h5-10H,1-4H3

171364-85-5 - Physico-chemical Properties

Molecular Formula	C15H18BNO2
Molar Mass	255.12
Density	1.10±0.1 g/cm3(Predicted)
Melting Point	56-60°C(lit.)
Boling Point	386.5±15.0 °C(Predicted)
Flash Point	187.53°C
Solubility	Chloroform (Slightly), Ethyl Acetate (Slightly)
Vapor Presure	0mmHg at 25°C
Appearance	Powder or Solid
Color	White to pale brown
pKa	5.12±0.12(Predicted)
Storage Condition	Refrigerator
Refractive Index	1.559
MDL	MFCD05155218
Physical and Chemical Properties	WGK Germany:3

171364-85-5 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3

171364-85-5 - Introduction

QUINOLINE-3-BORONIC ACID PINACOLATE is an organic compound with the chemical formula C12H12BClNO2. The following is a description of the properties, uses, preparation and safety information of the compound:

1. Nature:
-Appearance: QUINOLINE-3-BORONIC ACID PINACOLATE is a colorless to yellowish solid.
-Melting point: About 60-65 ℃.
-Solubility: Soluble in organic solvents such as ethanol and dichloromethane.
-Stability: relatively stable under normal temperature conditions.

2. Use:
- QUINOLINE-3-BORONIC ACID PINACOLATE is a pharmaceutical intermediate that can be used to synthesize various pharmaceutical compounds.
-can be used as borohydride reagent, effective borane reagent and reducing agent.

3. Preparation method:
-The synthesis of QUINOLINE-3-BORONIC ACID PINACOLATE is usually prepared by reacting quinoline-3-carboxylic ACID and pinacol Ester, and then adding tributyl borate to initiate the esterification reaction.

4. Safety Information:
- QUINOLINE-3-BORONIC the security of ACID PINACOLATE is high, the following matters still need to be paid attention:
-Avoid inhaling dust or contact with skin. Wear protective gloves and goggles when using.
-Avoid reacting with strong oxidants and strong acids.
-Operate in a well-ventilated place to avoid dust.
-In case of contact with skin or eyes, rinse immediately with water and seek medical advice.

Last Update：2024-04-09 02:00:43