172023-97-1

172023-97-1 - Names and Identifiers

Name	3-bromo-5-(trifluoromethyl)-benzenemethanol
Synonyms	3-BroMo-5-(trifluoroMethyl)benzyl acohol 3-BROMO-5-(TRIFLUOROMETHYL)BENZYL ALCOHOL 3-Bromo-5-(Trifluoromethyl)Benzyl Alcohol 3-Bromo-5-(trifluoromethyl)benzenemethanol 3-bromo-5-(trifluoromethyl)-benzenemethanol [3-BROMO-5-(TRIFLUOROMETHYL)PHENYL]METHANOL [3-Bromo-5-(trifluoromethyl)phenyl]methanol benzenemethanol, 3-bromo-5-(trifluoromethyl)- Benzenemethanol, 3-bromo-5-(trifluoromethyl)- (3-Bromo-5-(trifluoromethyl)phenyl)methanol M61623
CAS	172023-97-1
InChI	InChI=1/C8H6BrF3O/c9-7-2-5(4-13)1-6(3-7)8(10,11)12/h1-3,13H,4H2

172023-97-1 - Physico-chemical Properties

Molecular Formula	C8H6BrF3O
Molar Mass	255.03
Density	1.667g/cm³
Boling Point	243°C at 760 mmHg
Flash Point	100.8°C
Vapor Presure	0.0176mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.505

172023-97-1 - Introduction

3-bromo-5-(trifluoromethyl)-benzenemethanol is an organic compound with the chemical formula C8H7BrF3O.

Nature:
3-bromo-5-(trifluoromethyl)-benzenemethanol is a colorless liquid with a distinctive odor. It is an organofluorine compound with a high degree of chemical stability and inertness. It is soluble in organic solvents such as ethanol, dimethyl sulfoxide and dimethylformamide.

Use:
3-bromo-5-(trifluoromethyl)-benzenemethanol is an important organic synthesis intermediate, which is widely used in the manufacturing process of pesticides, fluorescent dyes, pharmaceuticals and flexible display materials. It can also be used in organic synthesis reactions, such as addition reactions, substitution reactions and hydroxyl protection reactions.

Method:
3-bromo-5-(trifluoromethyl)-benzenemethanol can be prepared by reacting benzyl alcohol with trifluoromethylmagnesium bromide. The specific step is to first react benzyl alcohol and trifluoromethylmagnesium bromide to form the corresponding alkyl magnesium bromide, and then react with bromine to form 3-bromo-5-(trifluoromethyl)-benzenemethanol.
The reaction equation is as follows:

C6H5CH2OH CF3MgBr → C6H5CH2CF3 MgBrOH
C6H5CH2CF3 Br2 → C6H4BrCF3CH2OH

Safety Information:
3-bromo-5-(trifluoromethyl)-benzenemethanol is relatively stable at room temperature, but decomposition reaction may occur at high temperature or in the presence of organic hydrogenation agent. It is an organic fluorine compound with certain toxicity. Attention should be paid to protective measures to avoid contact with skin and eyes. Use protective gloves, goggles and protective clothing during operation. If inhaled or ingested by mistake, you should seek medical treatment immediately.

Last Update：2024-04-09 02:00:43